I've been running my Prusa i3 MK3S+ for almost 5 years now. I don't run it 24/7 and mostly just design and print crap for around the house, 2a stuff, and just other random shit. But..
It's used, and often (printed straight for three weeks when I started getting into printing lowers - without one bag print)
I've only had to replace the bed temp sensor
Never have issues painting anything. It just works without any tinkering. Eats PLA, PLA+, PETG like nothing, all day long. I don't even remember the last time I got a bad print, must have been years ago...
My last print... Overture Super PLA Plus. Other than removing support, no cleanup was needed.