Wave,
As background, I've got a 6.8SPC upper from MSTN (18"), a JP Enterprises-built AR-10, a couple FAL's, and of course a bunch of 5.56 AR's.
The best justification is that it packs almost as much punch as the 308, but fits in the light, compact AR15 format. If you hunt, a nice little M4 can be your deer gun. For SHTF, home defense, or duty, you can forget all the "Is 5.56mm Good Enough?" questions, but keep the AR15 platform. A 115gr OTM or 110gr VMAX at 2650 - 2800fps will have superior terminal effects to M193 or M855.
Why not step up to the AR10? Set your AR10 next to an AR15, note the size difference. Note the weight difference. Field strip both rifles and set the AR10 bolt carrier assembly next to the AR15 bolt carrier assembly. Note that the AR10 assembly weighs at least 2x the AR15 assembly's weight. The is a huge difference in reciprocating mass; it's that inertia that makes split times on the AR10 longer.
-z