I'm by no means a V-22 expert, but as a helicopter pilot the V-22 design has always appeared to be a low margin design. Single points of failure combined with VRS and settling with power (over pitching) issues. Sure, it does cool stuff, but nothing is free. What it is capable of doing comes with some unique risks.
I'd love to see some statistics on V-22 accidents. Bet 90% of them fall into the aforementioned categories of single point failures and VRS/settling.