Big guns and recoil.
Having now had a moderate ammount of experience with a 470 NE and also a 458 Lott, my experience is that you get used to it. To some degree. The first shot was a totally new experience in recoil and of course caused some concern. But there was no real pain or lasting soreness. Each new range session was less and less intense. The jittery nervousness of anticipating a big explosion as the trigger is squeezed is now gone allowing me to concentrate on a good sight picture and making a good shot. So if a rifle fits you and you use good shooting technique and keep the number of rounds fired per range session down to a sensible number then you should be able to reset your recoil tolerance to a higher level.