Here's one of the setups I used a few years ago. It's just a regular desk.
Here's what I'm using now. This is an old computer desk.
I've added a couple of shelves and rearranged things, but the layout works pretty well with the smaller radios mounted under the shelves.
Same desk: Different layout...
ETA:
As stated above, you'll most likely want to keep your HF rig down at the bottom so you aren't having to hold your arm in the air to turn the dial.
Have room for a notepad to copy down calls, times, etc... for your log.
Think about the backside of the desk and how you will organize cables. Mine is currently a disorganized cluster of wires, cables, and cords that makes it a royal PITA to find or move anything.
Desk space - Go Deep. You'll need room for the radio, 6 inches or so of space behind it for coax, wires, etc..., a keyboard, mouse, and writing surface. Some of this will be offset to the side, but you'll NOT want your keyboard right up against the radio if you can help it. Also remember that your keyboard is usually about 4 inches from the edge of the desk to give you wrist a place to rest.
Going vertical with meters, clocks, switches, and smaller radios keeps everything within reach without cluttering up the desktop.