a good safe bolted to the floor, cameras.
Most thieves seem to be junkies that are looking for an easy grab and get out type score....contrary to internet lore they are not James bond types.
if you have guns/valuables unsecured...that's what they are taking.
remember people talk, so if you keep a shotgun by the door, your friends might casually mention it to someone who mentions it to someone who is in less then desirable circles, if your not home, lock your stuff up.