Agreed, looking at pictures people have posted of S&W revolvers on-line I'd definitely want to inspect the gun before I paid for it; like so many other companies these days they seem to be having QC problems. S&W are what I'm used to also so there's a lot to say for that. I know the ammo manufacturers are making "defensive" ammo for .22WMR and even .22LR and that it's pretty darn rare to get an ammo induced failure, when using quality ammo, but maybe because I'm middle aged, I just don't want a rimfire for a primary defensive gun even though I don't mind walking around in the woods with a .22LR (depending on where and what I'm doing obviously).
For some time now my 642 has been my primary hiking/backpacking/fishing/kayaking gun; it was one of my primary CCW carry guns for a long time and I shoot it well but times change. Light and compact, I'm comfortable with five rounds (and a reload) most places and I can load a CCI shotshell as the first round since curious water moccasins are a thing here.