I've only handled one PDP and never got the chance to shoot it.
I own 2 Sig P320 pistols and it is my favorite and go-to pistol for most things. It has been reliable, safe, and extremely accurate. I also love the almost infinite flexibility of the platform, and hope to purchase a Flux Raider Chassis at some point.
IMNSHO the Sig P320 is the AR15 of the Handgun world.