If you travel often, the easiest thing i have found to do is avoid programming in specific repeaters.
Instead, download all the repeaters in an area, sort by input / output freqs, and remove duplicate freqs. Then build your scan list and set every channel to output tone. (not tone squelch)
Using this method i have every 70cm and 2M repeater pair possible (except odd offsets) in the country programmed into my radio, and constantly on scan. Hit the mic stop button when something interesting is heard. Hit function -> tone scan to find the tone if i care to join in.
Considering repeaterbook often has dead repeaters anyway, i've found this to be the simplest way to provide easy coverage of all possibilities when not spending time in a specific area.