User Panel
Posted: 4/13/2023 3:03:53 PM EDT
Figured I'd share my experience with semaglutide.
Today marks about 30 days since I started. TL;DR: Lost about 20lbs and 3" of waist circumference. I got it from a telemedicine service and pay $250-450/month for the generic compounded drug. Side effects were pretty mild so far (diarrhea/indigestion). Used a service called Ivim Health. Telemedicine-only company that specializes in weight loss. They do seem a little bit "pill-mill" like, but they are at least board-certified doctors/NPs. I'm not necessarily recommending them, that just happens to be who I use. Process: Filled out a questionaire, booked an online telemedicine appointment for about 3 days later. Talked to the NP for 15-20 minutes or so. They told me I was a candidate and asked if I wanted to try it. They give you generic lab-compounded if you're paying cash (which I am), and the name-brand stuff if your insurance will cover it. For the generic, the first 3 Months = $750. Every other month = $425 (because you take more of the drug). You don't pay them anything for the appointments, all the costs are rolled into the price of the drug. You get titrated up from .25Mg to 2.5Mg to help prevent side effects. Week 1 - 4 is .25Mg, 4-8 is .5Mg, 8-12 is 1Mg, and 12+ is 2.5Mg (the full "maintenance" dose). If you use the generic, you just draw it out of a vial and inject it into some belly fat. You can get the tiny 31g insulin needles, which you can barely feel. The name-brand stuff has the fancy auto injector pen. I'm 35 and 5'10 - Each weigh in was taken with 2 digital scales (I don't trust the crappy Wal-Mart scales I have) Day 0: 268lbs Day 7: 262lbs Day 14: 257 Day 21: 254 Day 28: 249 Day 35: 245 Day 42: 241 |
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So, almost 20lbs of weight and 3" inches of waist circumference, granted a good chunk is probably "water weight." That seems impressive for only the first month, though everybody responds differently.
Eating I didn't make any real conscious effort to change my (obviously crappy) diet. The only exception is I tried to make sure I ate at least 100G of protein per day, I failed a lot of the time. For me, anyway, this stuff really works at curbing my apetite, even at the very low dose. For example, I remember a week after my first dose I heated up a bowl of canned chili (maybe 3/4 of a can). About halfway through it, I felt overwhelmingly full. Normally I could eat the whole bowl of chili and then have a bowl of cereal 15 minutes later. No way in hell I could do that with this stuff. Side Effects Diarrhea on 2 different days. Not too bad. All in all, I'm happy with it so far. From what the NP told me, at 5'10 and 260ish, I might have qualified to have my insurance cover it, but I have a high deductible plan, and I'd rather just pay cash and not worry about that BS. |
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You could just not eat as much. Rather than pay $2500 per year, you’d save money and probably live longer to enjoy the money you saved.
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My wife is on it to lower her A1C..she is 5'4" and went from 140 to 120 in 3 months..I call her face The O face now as she looks so gaunt...considering she still has DDD's..that weight loss in impressive
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Quoted: the shit people do to avoid eating healthy and exercising. View Quote I should start a service where people pay me to wear a body camera and I yell at them when they eat crap food and sit on their ass. I should probably outsource the yelling to a drill instructor for maximum impact.. |
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Quoted: They're going to make billions off of this. Users either have to learn to control their eating naturally, or else use wegovy for their entire life. View Quote View All Quotes View All Quotes Quoted: Quoted: the shit people do to avoid eating healthy and exercising. Getting down to a healthy weight and learning a healthy lifestyle, then weaning off, is the intent. You also have to break the addiction to food and resolve any underlying psychological issues, or it will come right back. Kharn |
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Here is further reading.
Article However, from the information we can scrape together based on sub-cohort data, these “miracle drugs” start to look a bit less miraculous. In 2021’s STEP 1 trial – the first trial demonstrating the efficacy of semaglutide as a treatment for adult obesity – a subset of 140 patients underwent DEXA scans for body composition analysis. Among these patients, lean mass accounted for approximately 39% of total weight loss – substantially higher than ideal. In a substudy of 178 patients from the SUSTAIN 8 trial on semaglutide as a diabetes treatment, the average proportion of lean mass loss was nearly identical at 40%, despite lower doses and less total weight loss than in the STEP 1 trial. View Quote As we’ve seen time and again, there are no such things as “miracle drugs,” and GLP-1 agonists are no exception to this rule. While they may have value for certain individuals, these medications come with downsides beyond their hefty price tag, and both physicians and patients ought to exercise extreme caution and discretion in determining whether they are truly the right choice for weight management. View Quote When we take body composition into factor, these people are getting lighter, but they're getting fatter. View Quote Dr Peter Attia, a physician based in Austin, Texas, warned the drugs were not a 'panacea' for weight loss — despite taking Hollywood by storm. He said that they prompted equal muscle-to-fat loss in patients, which he argued made them metabolically 'fatter' because they then had a higher fat-to-muscle percentage. View Quote Dr Attia giving a talk on it. |
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I started walking 4.5 mi per day and eating more sensibly. About 1500 cal. Exercise is worth about 500 cal and gives me a cushion for being inexact on eating. 10 lbs. in 30 days. 188 to 178. Going to see about 168. 5’11
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Quoted: Getting down to a healthy weight and learning a healthy lifestyle, then weaning off, is the intent. You also have to break the addiction to food and resolve any underlying psychological issues, or it will come right back. Kharn View Quote |
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Quoted: You could just not eat as much. Rather than pay $2500 per year, you’d save money and probably live longer to enjoy the money you saved. View Quote that's really the way I would try to go. from what I have been seeing people need to stay on the drug. Behavioral modification seems more effective and far less expensive. Easiest for me is just waiting as long as I can in the day till I actually feel hungry for more than a moment. Often make it all the way till dinner, sometimes a light afternoon snack to get me there and then I eat whatever the fuck I want and often follow up with a nice scoop of icecream. I'm 6'2 187 lbs. |
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Quoted: My wife is on it to lower her A1C..she is 5'4" and went from 140 to 120 in 3 months..I call her face The O face now as she looks so gaunt...considering she still has DDD's..that weight loss in impressive View Quote It was her high school reunion and she wore a pair of jeans from her high school days. She does keto to keep her 118-120lb weight. |
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View Quote That certainly hasn't been a noticeable problem for me, though I life heavy a few times per week. I can squat the same 425x5 that I could before I lost 20lbs. I've also lost a commensurate amount of waist circumference, which is indicative of fat loss, not muscle loss. Would the effects be the same on a completely sedentary person that doesn't move from their couch? I'm not sure. I simply refuse to believe that my body will store 80+ lbs of fat that it thinks it might need for a period of starvation, and then when the period of starvation comes, it uses my muscle tissue to fuel itself, the same muscle tissue I might need to "kill the mammoth for dinner." For me, and my admitted short-term experience with it, anyway, you could not argue that I'm less healthy than I was before I took it. |
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Quoted: Figured I'd share my experience with semaglutide. Today marks about 30 days since I started. TL;DR: Lost about 20lbs and 3" of waist circumference. I got it from a telemedicine service and pay $250-450/month for the generic compounded drug. Side effects were pretty mild so far (diarrhea/indigestion). Used a service called Ivim Health. Telemedicine-only company that specializes in weight loss. They do seem a little bit "pill-mill" like, but they are at least board-certified doctors/NPs. I'm not necessarily recommending them, that just happens to be who I use. Process: Filled out a questionaire, booked an online telemedicine appointment for about 3 days later. Talked to the NP for 15-20 minutes or so. They told me I was a candidate and asked if I wanted to try it. They give you generic lab-compounded if you're paying cash (which I am), and the name-brand stuff if your insurance will cover it. For the generic, the first 3 Months = $750. Every other month = $425 (because you take more of the drug). You don't pay them anything for the appointments, all the costs are rolled into the price of the drug. You get titrated up from .25Mg to 2.5Mg to help prevent side effects. Week 1 - 4 is .25Mg, 4-8 is .5Mg, 8-12 is 1Mg, and 12+ is 2.5Mg (the full "maintenance" dose). If you use the generic, you just draw it out of a vial and inject it into some belly fat. You can get the tiny 31g insulin needles, which you can barely feel. The name-brand stuff has the fancy auto injector pen. I'm 35 and 5'10 - Each weigh in was taken with 2 digital scales (I don't trust the crappy Wal-Mart scales I have) Day 0: 268lbs Day 7: 262lbs Day 14: 257 Day 21: 254 Day 28: 249 View Quote That would be an over dose of Ozempic. |
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Ozempic and other drugs like it are for Type 2 Diabetes. It just so happens that they aid in weight loss. So much so that there is a shortage of the medications. The medications are prescribed like candy to those that want to use it for weight loss. My wife has Type 2 Diabetes, and has had to miss dosses due to the local pharmacies being out. She has to shop the pharmacies to see which one has inventory so her prescription can be filled. While I hope the OP meets your weight loss goals. I am sure the OP can understand I will not have any sympathy for you if and when you get all the side effects of the drug.
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Quoted: *17th post too bad this stuff is for morbidly obese people, they need to make one tailored for the gym bro that needs to drop another ~5%-10% body fat to get visible abs. I'm a buyer for that lol View Quote I am 170 and need to cut 1-2 inches off my waist. wear 32" waist jeans but want my abs back, just can't work enough for the last bit. |
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This will blow up in y'all's (fat people's) faces eventually. Nothing in life is free. We'll just have a bunch of no muscle tone, skinny fat time bombs walking around feeling good until their strokes/heart attacks kill or cripple them.
"We don't know what happened? She was so thin!" a 300lb woman or 400lb man in a 120lb or 185lb body is still a weak, out of shape, unhealthy person. Enjoy! |
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Quoted: Yepp, I'm sure you're perfect and nothing is wrong in your life. Everything about you is 100% as good as it could be..... but only when you're posting anonymously on the internet of course, lol. View Quote Nobody's perfect, but self control is a lot cheaper. You'll lose total body mass, not just fat. Your in the early stages now, water weight and fluff. Once the fat is mostly gone your body will start eating the more important parts of itself. |
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Quoted: Ozempic and other drugs like it are for Type 2 Diabetes. It just so happens that they aid in weight loss. So much so that there is a shortage of the medications. The medications are prescribed like candy to those that want to use it for weight loss. My wife has Type 2 Diabetes, and has had to miss dosses due to the local pharmacies being out. She has to shop the pharmacies to see which one has inventory so her prescription can be filled. While I hope the OP meets your weight loss goals. I am sure the OP can understand I will not have any sympathy for you if and when you get all the side effects of the drug. View Quote I wasn't asking for any sympathy, guy. I was simply sharing my experience. I find it hilarious, though, that people with diabetes (most of them fat) are complaining about other fat people for buying "their" drug. But actually, I didn't buy "their" drug, because I got a generic from a compounding pharmacy, while most diabetics are getting name brand, since insurance typically won't cover the generic. I paid for the stuff just like everybody else. Care to make me a list of other stuff I shouldn't buy because it might inconvenience you? By the way, non-diabetics have to subsidize the health care costs of diabetics via their insurance premiums, just so you're aware. |
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Quoted: Nobody's perfect, but self control is a lot cheaper. You're losing total body mass, not just fat. View Quote And yet I'm much stronger (probably richer) than you are. How come you're not a billionaire that can deadlift 800lbs with a 30" waist? Why don't you get some self control? It's free after all. |
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Quoted: And yet I'm much stronger (probably richer) than you are. How come you're not a billionaire that can deadlift 800lbs with a 30" waist? Why don't you get some self control? It's free after all. View Quote View All Quotes View All Quotes Quoted: Quoted: Nobody's perfect, but self control is a lot cheaper. You're losing total body mass, not just fat. And yet I'm much stronger (probably richer) than you are. How come you're not a billionaire that can deadlift 800lbs with a 30" waist? Why don't you get some self control? It's free after all. Ooook, time to go back to Reddit/4chan, mr macho man |
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Quoted: And yet I'm much stronger (probably richer) than you are. How come you're not a billionaire that can deadlift 800lbs with a 30" waist? Why don't you get some self control? It's free after all. View Quote View All Quotes View All Quotes Quoted: Quoted: Nobody's perfect, but self control is a lot cheaper. You're losing total body mass, not just fat. And yet I'm much stronger (probably richer) than you are. How come you're not a billionaire that can deadlift 800lbs with a 30" waist? Why don't you get some self control? It's free after all. Rich guy? Your salt is showing. |
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Quoted: You get tit rated View Quote You can do that here for free. Post pics and we'll respond with pictures of various wooden things. |
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Quoted: Quoted: Figured I'd share my experience with semaglutide. Today marks about 30 days since I started. TL;DR: Lost about 20lbs and 3" of waist circumference. I got it from a telemedicine service and pay $250-450/month for the generic compounded drug. Side effects were pretty mild so far (diarrhea/indigestion). Used a service called Ivim Health. Telemedicine-only company that specializes in weight loss. They do seem a little bit "pill-mill" like, but they are at least board-certified doctors/NPs. I'm not necessarily recommending them, that just happens to be who I use. Process: Filled out a questionaire, booked an online telemedicine appointment for about 3 days later. Talked to the NP for 15-20 minutes or so. They told me I was a candidate and asked if I wanted to try it. They give you generic lab-compounded if you're paying cash (which I am), and the name-brand stuff if your insurance will cover it. For the generic, the first 3 Months = $750. Every other month = $425 (because you take more of the drug). You don't pay them anything for the appointments, all the costs are rolled into the price of the drug. You get titrated up from .25Mg to 2.5Mg to help prevent side effects. Week 1 - 4 is .25Mg, 4-8 is .5Mg, 8-12 is 1Mg, and 12+ is 2.5Mg (the full "maintenance" dose). If you use the generic, you just draw it out of a vial and inject it into some belly fat. You can get the tiny 31g insulin needles, which you can barely feel. The name-brand stuff has the fancy auto injector pen. I'm 35 and 5'10 - Each weigh in was taken with 2 digital scales (I don't trust the crappy Wal-Mart scales I have) Day 0: 268lbs Day 7: 262lbs Day 14: 257 Day 21: 254 Day 28: 249 That would be an over dose of Ozempic. "Ozempic requires you to increase dosage by two milligrams up to a max of eight milligrams, while Wegovy can only go up to a maximum of 2.4 milligrams on a weekly basis." Wegovy is for weight loss, Ozempic is for diabetes. Kharn |
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Quoted: *17th post too bad this stuff is for morbidly obese people, they need to make one tailored for the gym bro that needs to drop another ~5%-10% body fat to get visible abs. I'm a buyer for that lol View Quote This stuff is available online as a research chemical (semaglutide) if you're in to that sort of thing, which some gym bros are. |
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Damn, too late to make it in before all the “hUr dUr nO wILlpOwEr” crowd showed up.
OP. Good on you for taking charge of your health. Hopefully this springboards you to making and maintaining healthier lifestyle choices. |
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Quoted: Quoted: *17th post too bad this stuff is for morbidly obese people, they need to make one tailored for the gym bro that needs to drop another ~5%-10% body fat to get visible abs. I'm a buyer for that lol it works well for that too the data doesn't indicate that. I'm not giving up 40% of my gains in exchange for visible abs. I want a product where I give up NO lean mass.... I mean, a product that isn't Clen, Tren, & Test, cuz I also like being able to get erections. |
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Quoted: Damn, too late to make it in before all the “hUr dUr nO wILlpOwEr” crowd showed up. OP. Good on you for taking charge of your health. Hopefully this springboards you to making and maintaining healthier lifestyle choices. View Quote The first step towards better lifestyle choices rarely involves injecting unnecessary things into your body... |
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Quoted: Damn, too late to make it in before all the “hUr dUr nO wILlpOwEr” crowd showed up. OP. Good on you for taking charge of your health. Hopefully this springboards you to making and maintaining healthier lifestyle choices. View Quote Will power is a huge part of it though. Many just want the magic easy button and still want to eat like shit and not exercize. |
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Quoted: the data doesn't indicate that. I'm not giving up 40% of my gains in exchange for visible abs. I want a product where I give up NO lean mass.... I mean, a product that isn't Clen, Tren, & Test, cuz I also like being able to get erections. View Quote exercise. You must not know anything about PED's and clearly never been on a hefty dose of Test/Tren. |
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Quoted: exercise. You must not know anything about PED's and clearly never been on a hefty dose of Test/Tren. View Quote View All Quotes View All Quotes Quoted: Quoted: the data doesn't indicate that. I'm not giving up 40% of my gains in exchange for visible abs. I want a product where I give up NO lean mass.... I mean, a product that isn't Clen, Tren, & Test, cuz I also like being able to get erections. exercise. You must not know anything about PED's and clearly never been on a hefty dose of Test/Tren. I don't think you read my comment correctly. I mean I want a product that will drop 10% body fat, without losing lean mass (aka: gear); that also ISN'T gear - because I like to fuck. |
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Quoted: I don't think you read my comment correctly. I mean I want a product that will drop 10% body fat, without losing lean mass (aka: gear); that also ISN'T gear - because I like to fuck. View Quote I have watched some videos put out by a guy named Derek, he says you need to eat chicken breasts and broccoli. That’s what all the Hollywood action stars do. |
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Quoted: The first step towards better lifestyle choices rarely involves injecting unnecessary things into your body... View Quote View All Quotes View All Quotes Quoted: Quoted: Damn, too late to make it in before all the “hUr dUr nO wILlpOwEr” crowd showed up. OP. Good on you for taking charge of your health. Hopefully this springboards you to making and maintaining healthier lifestyle choices. The first step towards better lifestyle choices rarely involves injecting unnecessary things into your body... Who gives a shit. This is like the “learn to shoot with irons before using red dots” arguments. No. You can, in fact, be a competent shooter with irons even if you learn on red dots first. All this complaining about people using modern tools available to them to get on a path to being healthier reeks of virtue signaling. |
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Quoted: *17th post too bad this stuff is for morbidly obese people, they need to make one tailored for the gym bro that needs to drop another ~5%-10% body fat to get visible abs. I'm a buyer for that lol View Quote View All Quotes View All Quotes Quoted: Quoted: Interesting first post. *17th post too bad this stuff is for morbidly obese people, they need to make one tailored for the gym bro that needs to drop another ~5%-10% body fat to get visible abs. I'm a buyer for that lol I know a couple of folks who have done it. You just aren’t asking the right people. It will take a few months though and I understand that the acid reflux and stomach upset might not be worth it. |
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Quoted: Who gives a shit. This is like the “learn to shoot with irons before using red dots” arguments. No. You can, in fact, be a competent shooter with irons even if you learn on red dots first. All this complaining about people using modern tools available to them to get on a path to being healthier reeks of virtue signaling. View Quote 20lb of fluff didn't make OP unhealthy. What are the chances OP hits his weight goal using this "tool", discontinues use (since he's not diabetic and doesn't "need" it consistently) and then maintains that weight by making good choices? Possible? Sure Probable? Statically, no way. |
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