Injectable Peptides…for more than weight loss (Page 64 of 65)
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Originally Posted By -CRW-: I would say the 3 best things you can take for overall health and fitness is Testosterone - enough to be in the upper end of the reference range, Retatrutide, and a growth hormone releasing hormone - specifically CJC-1295 or Tesamorelin, and Ipamorelin to complement whichever of the first two you pick. I took Sermorelin off and on for several years through an absurdly overpriced compounding pharmacy but never felt like it did anything for me. It may have helped a nagging shoulder injury but it's hard for me to say since I was taking other things at the time. A few weeks ago I started Tesamorelin/Ipamorelin and the very first night I slept better than I had in a long time. And it's continued each subsequent night. I'm sleeping around 6 hours, waking up in my own without an alarm, and feel better than before taking it with 8+ hours of sleep. Just as a test, my son and brother are both using CJC/Ipa and are experiencing the same drastic improvement in their sleep quality. I also am a believer in GHK-Cu. My wife started first with that and after 8 weeks her skin looked radically better. She actually did Glow for 25 days, then Klow. She is in her 40's with multiple auto-immune diseases and tries all sorts of skin care products and nothing has worked like Glow/Klow did for her. We assume it's the GHK-Cu so she is switching to that next to see if she gets the same benefits without the add-ons in the blends. https://i.imgur.com/uunsNa2_d.webp?maxwidth=760&fidelity=grand Originally Posted By -CRW-: Originally Posted By 42ATK: So what are some other good peptides to consider with real science behind them? Reta seems like a slam dunk drug and the more I learn the more unbelievable it seems to be. What else is out there? My short list: - NAD+ - TB500/BPC157 (I might skip this due to cancer risks although they seem to be unfounded) I would say the 3 best things you can take for overall health and fitness is Testosterone - enough to be in the upper end of the reference range, Retatrutide, and a growth hormone releasing hormone - specifically CJC-1295 or Tesamorelin, and Ipamorelin to complement whichever of the first two you pick. I took Sermorelin off and on for several years through an absurdly overpriced compounding pharmacy but never felt like it did anything for me. It may have helped a nagging shoulder injury but it's hard for me to say since I was taking other things at the time. A few weeks ago I started Tesamorelin/Ipamorelin and the very first night I slept better than I had in a long time. And it's continued each subsequent night. I'm sleeping around 6 hours, waking up in my own without an alarm, and feel better than before taking it with 8+ hours of sleep. Just as a test, my son and brother are both using CJC/Ipa and are experiencing the same drastic improvement in their sleep quality. I also am a believer in GHK-Cu. My wife started first with that and after 8 weeks her skin looked radically better. She actually did Glow for 25 days, then Klow. She is in her 40's with multiple auto-immune diseases and tries all sorts of skin care products and nothing has worked like Glow/Klow did for her. We assume it's the GHK-Cu so she is switching to that next to see if she gets the same benefits without the add-ons in the blends. https://i.imgur.com/uunsNa2_d.webp?maxwidth=760&fidelity=grand |
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Originally Posted By W202fan90: Is there a post in this thread with a list of trusted sellers? I see ones advertising on Reddit, but I’d prefer a GD’ers recommendation. Get on STG's telegram and see whom they let advertise this week. They have a channel for sellers with US warehouse and testing groups. Lots of good vendors until they're not. |
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Originally Posted By tripntx: What is the proper way to deal with NAD+ BUFFERED when it has a pH of 3 after reconstitution? Does all NAD+ that is available to us in CONUS have a pH of 3 when reconstituted? My wife and I started the 14-Week Mitochondrial Protocol. Ordered a vial of 500mg NAD+ Buffered, several vials of 1,000 NAD+ Buffered, 12 vials SS31, and numerous MOTS-C. I reconned the 500mg NAD+ Buffered with 2ml Hospira BAC to begin the 25mg and then 50mg twice weekly first three weeks of the protocol. It was pure fire to inject. So much so that we couldn't do more than the first 25mg injection. I ordered pH strips after doing some research. It showed a pH of 3! So, I ordered injectable Sodium Bicarbonate and was able to buffer it to 7.4pH. Yesterday I reconned the first of several 1,000 NAD+ Buffered vials with 2ml BAC, then tested pH. It too tested at 3. I purposely only used 2ml BAC so that I'd have room to bring it to 3ml with either more BAC or by buffering. It took exactly 1ml injectable Sodium Bicarbonate to bring it from 3 to 7pH. I have reached out to the CONUS vendor who I purchase most of my peptides from, and they are 'looking' into it. BTW, thank you to the OP... I started reading this tread in March when I was prescribed Wegovy Tablets. In early May I transitioned to grey market TIRZ and RETA (thanks to this thread), and started using BPC157, both TB4 & TB500, KVP, PT-141, Testagen, KLOW 100 (blending myself with CHK-Cu KPV 50/20 blend vial, plus add another 10mg KPV, 10mg TB4, and 10mg BPC157 in 3ml Sodium Chloride BAC), NA Epitalon amidate, Kisspeptin, DSIP, TESA/IPA/CJCnoDAC 16/3/3 (blending myself with a vial of 6/3/3 and adding 10mg TESA in 2ml BAC for twice daily 1mg TESA injection), and then my final blended concoction of Cartalax/KVP/TB500/BPC157 40/10/10/10 in 3ml BAC. I have already cycled off some of the 20-day protocols. I'm late 50's, 5'6", currently 175#, testosterone was 370 in March (new draw in two days), IGF-1 was 0.2 before I started any of the HGH surrogate stuff (will have blood drawn in 4 weeks for new IGF-1). Real Enclomiphene 25mg tablets (not clomiphene) are arriving tomorrow, so I will begin 12.5mg daily after my blood draw for TEST and Estradiol is complete. I've been taking 12.5mg Enclomiphene two times a week for the past 4 to 5 weeks, and injecting TESA, IPA, and CJCnoDAC for the past 8 weeks. My numbers have really changed. Testosterone Total 454 to 1088 Testosterone Free 68.2 to 100.7 Testosterone Available 113.2 to 207.1 FSH and LH had never been analyzed before. Estradiol 33 to Estradiol US 55 Edited to add: I started taking 0.25mg Anastrozole once a week as soon as I saw the Estradiol number had increased. SHBG 29 to 59 DHEA-S had never been analyzed before. IGF-1 156 to 289 Z-Score 0.3 to 1.8 '@HappyCamel' feel free to give me your thoughts, not only on the TEST & IGF, but on glucose since I'm using TESA and RETA. Upper 50's, 5'6", 171 lbs.  |
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Originally Posted By tripntx: I've been taking 12.5mg Enclomiphene two times a week for the past 4 to 5 weeks, and injecting TESA, IPA, and CJCnoDAC for the past 8 weeks. My numbers have really changed. Testosterone Total 454 to 1088 Testosterone Free 68.2 to 100.7 Testosterone Available 113.2 to 207.1 FSH and LH had never been analyzed before. Estradiol 33 to Estradiol US 55 Edited to add: I started taking 0.25mg Anastrozole once a week as soon as I saw the Estradiol number had increased. SHBG 29 to 59 DHEA-S had never been analyzed before. IGF-1 156 to 289 Z-Score 0.3 to 1.8 '@HappyCamel' feel free to give me your thoughts, not only on the TEST & IGF, but on glucose since I'm using TESA and RETA. Upper 50's, 5'6", 171 lbs. https://www.ar15.com/media/mediaFiles/17671/Lab_tracking-3819250.png Script for Enclo or did you find it in the wild? |
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Originally Posted By AWMCoalition: Script for Enclo or did you find it in the wild? Originally Posted By AWMCoalition: Originally Posted By tripntx: I've been taking 12.5mg Enclomiphene two times a week for the past 4 to 5 weeks, and injecting TESA, IPA, and CJCnoDAC for the past 8 weeks. My numbers have really changed. Testosterone Total 454 to 1088 Testosterone Free 68.2 to 100.7 Testosterone Available 113.2 to 207.1 FSH and LH had never been analyzed before. Estradiol 33 to Estradiol US 55 Edited to add: I started taking 0.25mg Anastrozole once a week as soon as I saw the Estradiol number had increased. SHBG 29 to 59 DHEA-S had never been analyzed before. IGF-1 156 to 289 Z-Score 0.3 to 1.8 '@HappyCamel' feel free to give me your thoughts, not only on the TEST & IGF, but on glucose since I'm using TESA and RETA. Upper 50's, 5'6", 171 lbs. https://www.ar15.com/media/mediaFiles/17671/Lab_tracking-3819250.png Script for Enclo or did you find it in the wild? You can get Enclo pretty easily from algorx.ai. I use them for my bloodwork and it's pretty cheap. Under $100 for their full TRT panel with added lipids. I do use a coupon code, but its only 10% off I think. Generally get blood from them, and whatever meds are justifiable can be purchased right through the site. Pills only though, no oils. That said, you can just print the Quest/Labcorp report from their site and hand it on over to any other doc/TRT mill and they'll take care of you. Beats the hell out of otherwise paying 200+ for blood and getting literally the same exact report from the same company. Also- Taking an AI when E2's at 59... Isn't that not advisable unless you feel bad with your E2 there? It's certainly not danger territory. For reference, at 200mg/wk test c my E2 was 61 without an AI when I first started TRT. Leaned out a little bit and it dropped on its own (the E2). Never messed with an AI. I do feel better with my E2 in the 40-50 range. But I feel more switched on when it's lower than 60, I didn't feel like shit at 60. And definitely felt WAY better than I did when my total test was 220 and E2 was <30 |
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Originally Posted By AWMCoalition: Get on STG's telegram and see whom they let advertise this week. They have a channel for sellers with US warehouse and testing groups. Lots of good vendors until they're not. Originally Posted By AWMCoalition: Originally Posted By W202fan90: Is there a post in this thread with a list of trusted sellers? I see ones advertising on Reddit, but I’d prefer a GD’ers recommendation. Get on STG's telegram and see whom they let advertise this week. They have a channel for sellers with US warehouse and testing groups. Lots of good vendors until they're not. Some how I've only found out about STG tonight. I was WAAAAAAY overpaying for Reta  Hope "Elsa's" Reta is good for my research purposes 
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Originally Posted By tripntx: I've been taking 12.5mg Enclomiphene two times a week for the past 4 to 5 weeks, and injecting TESA, IPA, and CJCnoDAC for the past 8 weeks. My numbers have really changed. Testosterone Total 454 to 1088 Testosterone Free 68.2 to 100.7 Testosterone Available 113.2 to 207.1 FSH and LH had never been analyzed before. Estradiol 33 to Estradiol US 55 Edited to add: I started taking 0.25mg Anastrozole once a week as soon as I saw the Estradiol number had increased. SHBG 29 to 59 DHEA-S had never been analyzed before. IGF-1 156 to 289 Z-Score 0.3 to 1.8 '@HappyCamel' feel free to give me your thoughts, not only on the TEST & IGF, but on glucose since I'm using TESA and RETA. Upper 50's, 5'6", 171 lbs. https://www.ar15.com/media/mediaFiles/17671/Lab_tracking-3819250.png Unless you're having side affects, I wouldn't even sweat taking an AI with an E2 of 55... Actually probably more of a negative than help. |
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I will be doing a bunch of serious reading tomorrow for a purchase for a glp. I bought some from a place years ago and it worked, then another place and it did not. Send me any suggestions as to where to buy please. I will be doing the reading tomorrow on what to buy. I know I am going for tesa as I have visceral fat I need to get rid of and just need to figure out what else. |
"I am gonna laugh my ass off looking out the air vent of the box car watching some of you shot in the head in a ditch when you finally realize it's time to resist." stolen from RR_broccoli
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Originally Posted By tripntx: I've been taking 12.5mg Enclomiphene two times a week for the past 4 to 5 weeks, and injecting TESA, IPA, and CJCnoDAC for the past 8 weeks. My numbers have really changed. Testosterone Total 454 to 1088 Testosterone Free 68.2 to 100.7 Testosterone Available 113.2 to 207.1 FSH and LH had never been analyzed before. Estradiol 33 to Estradiol US 55 Edited to add: I started taking 0.25mg Anastrozole once a week as soon as I saw the Estradiol number had increased. SHBG 29 to 59 DHEA-S had never been analyzed before. IGF-1 156 to 289 Z-Score 0.3 to 1.8 '@HappyCamel' feel free to give me your thoughts, not only on the TEST & IGF, but on glucose since I'm using TESA and RETA. Upper 50's, 5'6", 171 lbs. https://www.ar15.com/media/mediaFiles/17671/Lab_tracking-3819250.png You said youre on Retatrutide but your A1C is 5.6 and you have an average daily glucose of 116. Thats a bit much, even if youre carrying a little extra weight (based on 5'6" / 171 lbs). If you are just lean and muscular, its a bigger problem, actually. 5.7 is the top of the reference range, but youre taking a GLP, so id expect that you would be around 6.0 A1C without it. 5.6 is not an "I'm ok, its in the range" number, either. Glucose disposal doesnt work that way. Its an unhealthy marker, IMO. Take that for what its worth, im not a doctor. At the very least, id cut off the Ipamorelin and CJC-1295. If you dont really want to do that, you need to at least get your diet in order. Carbohydrate intake is the easy lever to pull here. A caloric deficit might bring you down, its much less easy, though. I dont know how much you exercise. If its below average, fix that too. Youre really taking a ton of shit there, its good that you are on top of your labs. |
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Originally Posted By TurkeyLeg: I always harp on this, because its the only set of biomarkers i truly understand, but youre probably prediabetic. You said youre on Retatrutide but your A1C is 5.6 and you have an average daily glucose of 116. Thats a bit much, even if youre carrying a little extra weight (based on 5'6" / 171 lbs). If you are just lean and muscular, its a bigger problem, actually. 5.7 is the top of the reference range, but youre taking a GLP, so id expect that you would be around 6.0 A1C without it. 5.6 is not an "I'm ok, its in the range" number, either. Glucose disposal doesnt work that way. Its an unhealthy marker, IMO. Take that for what its worth, im not a doctor. At the very least, id cut off the Ipamorelin and CJC-1295. If you dont really want to do that, you need to at least get your diet in order. Carbohydrate intake is the easy lever to pull here. A caloric deficit might bring you down, its much less easy, though. I dont know how much you exercise. If its below average, fix that too. Youre really taking a ton of shit there, its good that you are on top of your labs. Thank you to those who have replied about AI's, as well as to the author of the post I'm quoting. My A1C had been running even higher the past several years. I retired more than 14 months ago. Started doing cardio 4 days a week for a year. Only lost from 205 to 198. You'll read why in the next paragraph. Started GLP-1 end of March 2026 and started doing cardio 6 days a week. GLP-1's cut my 4.5 oz sipping Tequila habit four nights a week to only one or less nights a week and dropped it from 4.5 oz to less than 3 oz when I do partake. I didn't realize how much neat clear/amber liquors was preventing me from losing weight. I've been tracking my weight daily for months on a smart scale. If I partake in liquor two nights in a row, then it takes three days of not having any before I start losing again. This has been a real eye opener. Have dropped from 198 to 171. I'm not lean and muscular, yet, but working on it. Six weeks ago, added in dumbbell strength training 3 days a week, hitting all the muscle groups. I did a DEXA scan a couple of months ago and found out I have 3.1 lbs visceral fat to lose, so I'll be on TESA for 6 months. I used a Stela glucose monitor for 15 days last month. It helped me dial in my eating habits much better. I learned adding 30+ grams of fiber to my diet helps tremendously, as well as a short walk after every meal. The majority of my carbs come from fiber &/or fruit based. I avoid intaking added sugars. My glucose runs low 100's, even overnight. They only times it dropped below 95 was if I had low carb meals (carbs & fats) without fiber, then it would climb towards 140 for a spike, and then crash down to 75 before rebounding to near 100. Another thought on the Stela, it helped determine that dinner by 1830 meant my glucose was back to normal by 2030 hrs, so taking TESA 2130 hrs was viable. Now to what I'm currently taking. KLOW 80 with extra 10 mg KPV and 50 mg GHK basic added to the vial. 2mg four days a week. 75mg NAD+ and 5mg MOTSC three days a week. Have 5 more weeks to go, then will cycle off these for at least six months. 1.5mg RETA twice a week. Kisspeptin 200mcg nightly. Have 4 more weeks to go, then will cycle off for four months. 1mg TESA twice a day, AM & PM. Now to the IPA & CJC. I need to mix more to continue these. I had been thinking about dropping CJC but continuing with IPA. I had seen your and others posts in this thread before about insulin resistance, so that has been in my thought process. Considering my activity level and diet, do any of you who really study glucose know if my situation warrants dropping both CJC & IPA, or continuing on them? I like having my IGF-1 at the higher end of my age group, but I do want to correct my pre-diabetes status. I'm sure my pre-diabetes will continue to get better as I lose more fat and add more muscle. |
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Originally Posted By tripntx: I've been taking 12.5mg Enclomiphene two times a week for the past 4 to 5 weeks, and injecting TESA, IPA, and CJCnoDAC for the past 8 weeks. My numbers have really changed. Testosterone Total 454 to 1088 Testosterone Free 68.2 to 100.7 Testosterone Available 113.2 to 207.1 FSH and LH had never been analyzed before. Estradiol 33 to Estradiol US 55 Edited to add: I started taking 0.25mg Anastrozole once a week as soon as I saw the Estradiol number had increased. SHBG 29 to 59 DHEA-S had never been analyzed before. IGF-1 156 to 289 Z-Score 0.3 to 1.8 '@HappyCamel' feel free to give me your thoughts, not only on the TEST & IGF, but on glucose since I'm using TESA and RETA. Upper 50's, 5'6", 171 lbs. https://www.ar15.com/media/mediaFiles/17671/Lab_tracking-3819250.png Originally Posted By tripntx: Originally Posted By tripntx: What is the proper way to deal with NAD+ BUFFERED when it has a pH of 3 after reconstitution? Does all NAD+ that is available to us in CONUS have a pH of 3 when reconstituted? My wife and I started the 14-Week Mitochondrial Protocol. Ordered a vial of 500mg NAD+ Buffered, several vials of 1,000 NAD+ Buffered, 12 vials SS31, and numerous MOTS-C. I reconned the 500mg NAD+ Buffered with 2ml Hospira BAC to begin the 25mg and then 50mg twice weekly first three weeks of the protocol. It was pure fire to inject. So much so that we couldn't do more than the first 25mg injection. I ordered pH strips after doing some research. It showed a pH of 3! So, I ordered injectable Sodium Bicarbonate and was able to buffer it to 7.4pH. Yesterday I reconned the first of several 1,000 NAD+ Buffered vials with 2ml BAC, then tested pH. It too tested at 3. I purposely only used 2ml BAC so that I'd have room to bring it to 3ml with either more BAC or by buffering. It took exactly 1ml injectable Sodium Bicarbonate to bring it from 3 to 7pH. I have reached out to the CONUS vendor who I purchase most of my peptides from, and they are 'looking' into it. BTW, thank you to the OP... I started reading this tread in March when I was prescribed Wegovy Tablets. In early May I transitioned to grey market TIRZ and RETA (thanks to this thread), and started using BPC157, both TB4 & TB500, KVP, PT-141, Testagen, KLOW 100 (blending myself with CHK-Cu KPV 50/20 blend vial, plus add another 10mg KPV, 10mg TB4, and 10mg BPC157 in 3ml Sodium Chloride BAC), NA Epitalon amidate, Kisspeptin, DSIP, TESA/IPA/CJCnoDAC 16/3/3 (blending myself with a vial of 6/3/3 and adding 10mg TESA in 2ml BAC for twice daily 1mg TESA injection), and then my final blended concoction of Cartalax/KVP/TB500/BPC157 40/10/10/10 in 3ml BAC. I have already cycled off some of the 20-day protocols. I'm late 50's, 5'6", currently 175#, testosterone was 370 in March (new draw in two days), IGF-1 was 0.2 before I started any of the HGH surrogate stuff (will have blood drawn in 4 weeks for new IGF-1). Real Enclomiphene 25mg tablets (not clomiphene) are arriving tomorrow, so I will begin 12.5mg daily after my blood draw for TEST and Estradiol is complete. I've been taking 12.5mg Enclomiphene two times a week for the past 4 to 5 weeks, and injecting TESA, IPA, and CJCnoDAC for the past 8 weeks. My numbers have really changed. Testosterone Total 454 to 1088 Testosterone Free 68.2 to 100.7 Testosterone Available 113.2 to 207.1 FSH and LH had never been analyzed before. Estradiol 33 to Estradiol US 55 Edited to add: I started taking 0.25mg Anastrozole once a week as soon as I saw the Estradiol number had increased. SHBG 29 to 59 DHEA-S had never been analyzed before. IGF-1 156 to 289 Z-Score 0.3 to 1.8 '@HappyCamel' feel free to give me your thoughts, not only on the TEST & IGF, but on glucose since I'm using TESA and RETA. Upper 50's, 5'6", 171 lbs. https://www.ar15.com/media/mediaFiles/17671/Lab_tracking-3819250.png First of all, get off the enclomiphene. You said you late 50s, I'm guessing you and your wife aren't trying for more kids. You're clearly comfortable with needles, just take test. If you don't want to use big needles...you don't have to . https://www.ar15.com/forums/general/PSA-DVT-Pulmonary-Embolisms-Warning-Graphic/5-2854551/?r=-1&page=1&anc=117385684#i117385684 As far as igf/z-score, 1.8 is solid unless you're a competitive athlete, but I'll circle back to how you're getting there in a moment. First of all, you're taking a metric fuckton of shit. While most of this stuff is generally recognized as safe (GRAS), that ignores polypharmacy...of which you are way in the deep end. This looks like a competitive bodybuilders stack that feels stuck at 300lbs and can't figure out how to grow more. Just because something or a protocol is good, doesn't mean everything at once is great. As far as your approach to igf, this is not optimal. To obtain a 1.8 z-score, you're on 3 secretagogues, and above the FDA prescribed daily dose of Egrifta (tesamorelin). So as I say almost every page here, the older you are, the less likely it is that secretagogues are going to be effective. Guys... just take plain old bioidentical HGH. Finally as far as A1c and glucose, I'll respond to that by continuing from the other guys comment. |
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Originally Posted By slowkota1: Some how I've only found out about STG tonight. I was WAAAAAAY overpaying for Reta Hope "Elsa's" Reta is good for my research purposes Originally Posted By slowkota1: Originally Posted By AWMCoalition: Originally Posted By W202fan90: Is there a post in this thread with a list of trusted sellers? I see ones advertising on Reddit, but I’d prefer a GD’ers recommendation. Get on STG's telegram and see whom they let advertise this week. They have a channel for sellers with US warehouse and testing groups. Lots of good vendors until they're not. Some how I've only found out about STG tonight. I was WAAAAAAY overpaying for Reta Hope "Elsa's" Reta is good for my research purposes Haven't heard anything bad about them recently. Glad you found them so you can stop being fleeced by the easy to use websites with ridiculous prices. |
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Originally Posted By TurkeyLeg: I always harp on this, because its the only set of biomarkers i truly understand, but youre probably prediabetic. You said youre on Retatrutide but your A1C is 5.6 and you have an average daily glucose of 116. Thats a bit much, even if youre carrying a little extra weight (based on 5'6" / 171 lbs). If you are just lean and muscular, its a bigger problem, actually. 5.7 is the top of the reference range, but youre taking a GLP, so id expect that you would be around 6.0 A1C without it. 5.6 is not an "I'm ok, its in the range" number, either. Glucose disposal doesnt work that way. Its an unhealthy marker, IMO. Take that for what its worth, im not a doctor. At the very least, id cut off the Ipamorelin and CJC-1295. If you dont really want to do that, you need to at least get your diet in order. Carbohydrate intake is the easy lever to pull here. A caloric deficit might bring you down, its much less easy, though. I dont know how much you exercise. If its below average, fix that too. Youre really taking a ton of shit there, its good that you are on top of your labs. Originally Posted By TurkeyLeg: Originally Posted By tripntx: I've been taking 12.5mg Enclomiphene two times a week for the past 4 to 5 weeks, and injecting TESA, IPA, and CJCnoDAC for the past 8 weeks. My numbers have really changed. Testosterone Total 454 to 1088 Testosterone Free 68.2 to 100.7 Testosterone Available 113.2 to 207.1 FSH and LH had never been analyzed before. Estradiol 33 to Estradiol US 55 Edited to add: I started taking 0.25mg Anastrozole once a week as soon as I saw the Estradiol number had increased. SHBG 29 to 59 DHEA-S had never been analyzed before. IGF-1 156 to 289 Z-Score 0.3 to 1.8 '@HappyCamel' feel free to give me your thoughts, not only on the TEST & IGF, but on glucose since I'm using TESA and RETA. Upper 50's, 5'6", 171 lbs. https://www.ar15.com/media/mediaFiles/17671/Lab_tracking-3819250.png You said youre on Retatrutide but your A1C is 5.6 and you have an average daily glucose of 116. Thats a bit much, even if youre carrying a little extra weight (based on 5'6" / 171 lbs). If you are just lean and muscular, its a bigger problem, actually. 5.7 is the top of the reference range, but youre taking a GLP, so id expect that you would be around 6.0 A1C without it. 5.6 is not an "I'm ok, its in the range" number, either. Glucose disposal doesnt work that way. Its an unhealthy marker, IMO. Take that for what its worth, im not a doctor. At the very least, id cut off the Ipamorelin and CJC-1295. If you dont really want to do that, you need to at least get your diet in order. Carbohydrate intake is the easy lever to pull here. A caloric deficit might bring you down, its much less easy, though. I dont know how much you exercise. If its below average, fix that too. Youre really taking a ton of shit there, its good that you are on top of your labs. I will agree that if it trends up from here it likely needs to be addressed, at a minimum dropping the igf stack, and if he wants to prevent getting there, pull the carb lever now. And yeah the AI is likely un-needed, but I like that you kept tabs on how you felt at different levels. If you got off enclo and went to test your estrogen would probably be right where you want it with no AI. |
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Originally Posted By tripntx: Thank you to those who have replied about AI's, as well as to the author of the post I'm quoting. My A1C had been running even higher the past several years. I retired more than 14 months ago. Started doing cardio 4 days a week for a year. Only lost from 205 to 198. You'll read why in the next paragraph. Started GLP-1 end of March 2026 and started doing cardio 6 days a week. GLP-1's cut my 4.5 oz sipping Tequila habit four nights a week to only one or less nights a week and dropped it from 4.5 oz to less than 3 oz when I do partake. I didn't realize how much neat clear/amber liquors was preventing me from losing weight. I've been tracking my weight daily for months on a smart scale. If I partake in liquor two nights in a row, then it takes three days of not having any before I start losing again. This has been a real eye opener. Have dropped from 198 to 171. I'm not lean and muscular, yet, but working on it. Six weeks ago, added in dumbbell strength training 3 days a week, hitting all the muscle groups. I did a DEXA scan a couple of months ago and found out I have 3.1 lbs visceral fat to lose, so I'll be on TESA for 6 months. I used a Stela glucose monitor for 15 days last month. It helped me dial in my eating habits much better. I learned adding 30+ grams of fiber to my diet helps tremendously, as well as a short walk after every meal. The majority of my carbs come from fiber &/or fruit based. I avoid intaking added sugars. My glucose runs low 100's, even overnight. They only times it dropped below 95 was if I had low carb meals (carbs & fats) without fiber, then it would climb towards 140 for a spike, and then crash down to 75 before rebounding to near 100. Another thought on the Stela, it helped determine that dinner by 1830 meant my glucose was back to normal by 2030 hrs, so taking TESA 2130 hrs was viable. Now to what I'm currently taking. KLOW 80 with extra 10 mg KPV and 50 mg GHK basic added to the vial. 2mg four days a week. 75mg NAD+ and 5mg MOTSC three days a week. Have 5 more weeks to go, then will cycle off these for at least six months. 1.5mg RETA twice a week. Kisspeptin 200mcg nightly. Have 4 more weeks to go, then will cycle off for four months. 1mg TESA twice a day, AM & PM. Now to the IPA & CJC. I need to mix more to continue these. I had been thinking about dropping CJC but continuing with IPA. I had seen your and others posts in this thread before about insulin resistance, so that has been in my thought process. Considering my activity level and diet, do any of you who really study glucose know if my situation warrants dropping both CJC & IPA, or continuing on them? I like having my IGF-1 at the higher end of my age group, but I do want to correct my pre-diabetes status. I'm sure my pre-diabetes will continue to get better as I lose more fat and add more muscle. |
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Originally Posted By CuldesacWarlord: You can get Enclo pretty easily from algorx.ai. I use them for my bloodwork and it's pretty cheap. Under $100 for their full TRT panel with added lipids. I do use a coupon code, but its only 10% off I think. Generally get blood from them, and whatever meds are justifiable can be purchased right through the site. Pills only though, no oils. That said, you can just print the Quest/Labcorp report from their site and hand it on over to any other doc/TRT mill and they'll take care of you. Beats the hell out of otherwise paying 200+ for blood and getting literally the same exact report from the same company. Also- Taking an AI when E2's at 59... Isn't that not advisable unless you feel bad with your E2 there? It's certainly not danger territory. For reference, at 200mg/wk test c my E2 was 61 without an AI when I first started TRT. Leaned out a little bit and it dropped on its own (the E2). Never messed with an AI. I do feel better with my E2 in the 40-50 range. But I feel more switched on when it's lower than 60, I didn't feel like shit at 60. And definitely felt WAY better than I did when my total test was 220 and E2 was <30 When my E2 gets into the high 50s, my sex drive plummets and my joint paint shoots up. There's going to be some individual variables of course, but in general I shoot for sub-50s. For reference, I'm on subQ TRT, max ranges on all the labs (total, free, %) so my E2 is in line with that being high reference. I could cut down the TRT but I'm happy where I'm at otherwise. |
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Originally Posted By HappyCamel: Switch your cardio to daily fasted cardio in the morning, you don't need more than 20-30min, zone 2, just wake up and do it. Between that and lowering carbs you'll probably see glucose and A1c shift down. Thanks to everyone who replied. I appreciate the engagement. Morning routine is coffee, peptides, cardio, then breakfast. HappyCamel, I'm sending you a message. |
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Originally Posted By HappyCamel: Paradoxically, you'll see raised A1c and glucose in many people on reta as the glucagon activation increases free fatty acids in the blood. It's generally more of a red herring and a net benefit to weight loss, but I maintain that Tirz is a superior compound for the majority of people. Reta got popular due to its minimal appetite suppression, so bodybuilders could eat through it to hit their caloric needs, and the gen pop crowd followed along even though they have a different set of needs. I will agree that if it trends up from here it likely needs to be addressed, at a minimum dropping the igf stack, and if he wants to prevent getting there, pull the carb lever now. And yeah the AI is likely un-needed, but I like that you kept tabs on how you felt at different levels. If you got off enclo and went to test your estrogen would probably be right where you want it with no AI. The medication has had a significant effect on my glucose from day one, but I agree that the liberation of fatty acids could easily cause an increase in glucose markers in people who are not insulin resistant. Since Im a diabetic, the condition of my beta cells and my overall insulin response is sub par, so the glucagon agonism isnt going to move the needle as much for someone like me (as fas as glucose is concerned). The interesting thing is that starting with 1 mg of Reta, I see a massive clamping effect whenever I start running. At mile one, my glucose is diving for 60-70 mg / dl. It never makes it to a level of hypoglycemia where i notice any side effects, and it claws its way back to the 80's by mile 5. Previously, before Reta, my runs resulted in a spike that was proportional to effort and stress. Essentially, hepatic glucose overran GLUT-4 transport and natural glucose disposal. This was worse in PR-type efforts and definitely in races. I took two small gels (20g of carbs) at my first race, a half marathon, and glucose was way up there, 220 or so. Compare that with a normal-ish run on Reta, where i had to eat some carbs on the run just to keep my glucose up. The prevailing theory is that the glp/gip agonism clamps the hepatic release via more aggressive insulin release and a few other things. Attached File Attached File Amazing pharmacology. Gotta ditch it soon though, its had a distinct effect on endurance and that wont fly for my winter training block. |
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First apologies if this was discussed previously in this thread. I've been in and out of it and haven't followed each and every post. Second this was posted over in Teams, then I remembered this thread as I was once right on the verge of ordering from some suppliers listed here and this suddenly became an easy way out.  Just a heads up for anyone that might currently or soon to be on Medicare. If your Dr agrees to write you a script, you can get in on a pilot program for GLP-1's for around $50 a month. Normally MC doesn't pay for GLP-1 unless you are diagnosed diabetic or something similar is the way I used to understand it. They are experimenting with this program to see if the effects of the weight loss will give overall benefits to other conditions. It doesn't need to be because you are a diabetic, general weight loss will qualify. I have BP that's been creeping up and despite being careful with diet and working out, the last of the weight gain just isn't budging. My GP told me about it about a week ago, started Zepbound last Friday. It went through "the process" faster than I expected. Medicare "Bridge" program for GLP-1 It's another option if you are on MC. |
There's nothing wrong with a little personal baggage, it's owning the whole luggage store that's the problem.
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I'm at the "research and see if this makes sense for me" phase. I'm 6'1, 220-225 lbs. I travel for 2 months at a time, usually twice a year, internationally. Obviously, taking grey-market substances with me on trips like that is a no-go. Is there any problem with taking it while I'm home for 4 months, then taking a break over a trip, then resuming another 4 months? This sounds like it could be harmful to cycle on and off like that, and likely overall ineffective? |
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Originally Posted By DDiggler: I'm at the "research and see if this makes sense for me" phase. I'm 6'1, 220-225 lbs. I travel for 2 months at a time, usually twice a year, internationally. Obviously, taking grey-market substances with me on trips like that is a no-go. Is there any problem with taking it while I'm home for 4 months, then taking a break over a trip, then resuming another 4 months? This sounds like it could be harmful to cycle on and off like that, and likely overall ineffective? 2. What peptide are you even talking about? |
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Originally Posted By HappyCamel: 1. It's perfectly fine unless it's a select few countries, were not talking about a controlled substance. Although some countries prohibit syringes coming in, like Japan. 2. What peptide are you even talking about? Originally Posted By HappyCamel: Originally Posted By DDiggler: I'm at the "research and see if this makes sense for me" phase. I'm 6'1, 220-225 lbs. I travel for 2 months at a time, usually twice a year, internationally. Obviously, taking grey-market substances with me on trips like that is a no-go. Is there any problem with taking it while I'm home for 4 months, then taking a break over a trip, then resuming another 4 months? This sounds like it could be harmful to cycle on and off like that, and likely overall ineffective? 2. What peptide are you even talking about? 1. One of the places I visit is Singapore, extremely strict and not worth the risk for me. I won't have a prescription, so... 2. I started by researching retatrutide... but I'm still learning as to what might work best for me. |
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Originally Posted By DDiggler: 1. One of the places I visit is Singapore, extremely strict and not worth the risk for me. I won't have a prescription, so... 2. I started by researching retatrutide... but I'm still learning as to what might work best for me. Originally Posted By DDiggler: Originally Posted By HappyCamel: Originally Posted By DDiggler: I'm at the "research and see if this makes sense for me" phase. I'm 6'1, 220-225 lbs. I travel for 2 months at a time, usually twice a year, internationally. Obviously, taking grey-market substances with me on trips like that is a no-go. Is there any problem with taking it while I'm home for 4 months, then taking a break over a trip, then resuming another 4 months? This sounds like it could be harmful to cycle on and off like that, and likely overall ineffective? 2. What peptide are you even talking about? 1. One of the places I visit is Singapore, extremely strict and not worth the risk for me. I won't have a prescription, so... 2. I started by researching retatrutide... but I'm still learning as to what might work best for me. |
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Originally Posted By HappyCamel: Your BMI at 225 is 29 which is overweight...BMI of 30 is Obese and a doctor could prescribe to you. If you have sleep apnea, HBP, ECT that + overweight qualifies you as well. Or you can go through a clinic and they may be more lax with prescribing guidelines. But no, going on and off for 4 months is not ideal. Singapore has fantastic food, you'd probably rebound like a MF Honestly, I enjoy my meals when I'm traveling and don't restrict myself much, but the daily walking as a necessary part of the routine plus what seems to be a better quality of food... I don't gain when I'm traveling, and sometimes lose. |
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First dose of tesa tonight, gonna do a 1/2 dose for 2 days to check for a reaction. Then Monday I start on tirz, so lets hope for the best. I have done semi before, I weigh 200 and I am 5'9. Most of it is my gut, I don't drink so thats not it. The gut is why I am adding the tesa and do the tirz at the same time. I was happy-ish at 183 when I did the semi, took me 3 years to get back to the 200lbs. Honestly gonna aim for 175, and will be doing some minor weights at home to keep muscle mass. |
"I am gonna laugh my ass off looking out the air vent of the box car watching some of you shot in the head in a ditch when you finally realize it's time to resist." stolen from RR_broccoli
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Originally Posted By ChuckD05: 10mg as in like $65/10mg vial?  Yeah. It varied slightly but usually between $65-75 for a 10mg vial. Can't remember the name off hand, I'll look when I get home. Iirc it was an AUS based company but everything shipped from TX. There still in business but no longer ship to the USA. Found it. It was peptilabresearch.co.m but appears to be a dead link now. Dunno why they closed down to the USA. Never had any issues & prices where great. |
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Originally Posted By Asylum9: Yeah. It varied slightly but usually between $65-75 for a 10mg vial. Can't remember the name off hand, I'll look when I get home. Iirc it was an AUS based company but everything shipped from TX. There still in business but no longer ship to the USA. Found it. It was peptilabresearch.co.m but appears to be a dead link now. Dunno why they closed down to the USA. Never had any issues & prices where great. Originally Posted By Asylum9: Originally Posted By ChuckD05: 10mg as in like $65/10mg vial? Yeah. It varied slightly but usually between $65-75 for a 10mg vial. Can't remember the name off hand, I'll look when I get home. Iirc it was an AUS based company but everything shipped from TX. There still in business but no longer ship to the USA. Found it. It was peptilabresearch.co.m but appears to be a dead link now. Dunno why they closed down to the USA. Never had any issues & prices where great. That emoji was because you were being ripped off. Nexaph, which is the high end of reputable places, has ten vials of 10mg for ~$250. |
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Originally Posted By HappyCamel: Cashapp will shut down your account the first or second time you send it to a peptide wholesale place. To maintain access to your Cashapp "on ramp", you send from Cashapp to an Exodus wallet, and from there to the final place. Do not send crypto from a KYC account to a seller. Always use non-KYC self-custody wallet as intermediary. @HappyCamel Tried creating an Exodus account yesterday. Was getting error messages and unable to complete verification. Sent an email to customer service and this was the response: “Our engineers have identified an ongoing issue affecting Exodus Pay card creation for U.S. users. We’re actively working on a fix and hope to have U.S. card issuance restored as soon as possible. We'll reach back out to you as soon as your card is available!” Thoughts? |
"I see dumb people... they're everywhere. They walk around like everyone else. They don't even know that they're dumb."
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Originally Posted By tonysoprano150: @HappyCamel Tried creating an Exodus account yesterday. Was getting error messages and unable to complete verification. Sent an email to customer service and this was the response: "Our engineers have identified an ongoing issue affecting Exodus Pay card creation for U.S. users. We're actively working on a fix and hope to have U.S. card issuance restored as soon as possible. We'll reach back out to you as soon as your card is available!" Thoughts? Originally Posted By tonysoprano150: Originally Posted By HappyCamel: Cashapp will shut down your account the first or second time you send it to a peptide wholesale place. To maintain access to your Cashapp "on ramp", you send from Cashapp to an Exodus wallet, and from there to the final place. Do not send crypto from a KYC account to a seller. Always use non-KYC self-custody wallet as intermediary. @HappyCamel Tried creating an Exodus account yesterday. Was getting error messages and unable to complete verification. Sent an email to customer service and this was the response: "Our engineers have identified an ongoing issue affecting Exodus Pay card creation for U.S. users. We're actively working on a fix and hope to have U.S. card issuance restored as soon as possible. We'll reach back out to you as soon as your card is available!" Thoughts? Plain old Exodus app, no cards ETA: there should be zero PID put into the app |
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Originally Posted By HappyCamel: I'm super confused because IDK wtf Exodus card is. Also, if they added a debit card, that sounds like you just put in KYC information.... Plain old Exodus app, no cards ETA: there should be zero PID put into the app I’m not sure either, as I didn’t apply for a card. But I went back into the app just now, and it says “verification complete” and lets me add funds. |
"I see dumb people... they're everywhere. They walk around like everyone else. They don't even know that they're dumb."
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Originally Posted By tonysoprano150: I’m not sure either, as I didn’t apply for a card. But I went back into the app just now, and it says “verification complete” and lets me add funds. Originally Posted By tonysoprano150: Originally Posted By HappyCamel: I'm super confused because IDK wtf Exodus card is. Also, if they added a debit card, that sounds like you just put in KYC information.... Plain old Exodus app, no cards ETA: there should be zero PID put into the app I’m not sure either, as I didn’t apply for a card. But I went back into the app just now, and it says “verification complete” and lets me add funds. Its part of their new Exodus Pay platform that they're pimping heavily here lately. I X this out every time I go into Exodus but its right back on there next time. Its an actual physical card tied to your Exodus wallet Attached File |
| I started on monday with first grey market peptide injections. CJC/Ipo. I am using a pen. I screwed up filling the cartridge. So basically wasted a vial. I saw a youtube that they pushed the stopped up before filling so you don't have to use a vent. It ended up pushing the stopper out the bottom and wasting it. So I used a needle to vent for the next one. Easy. |
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Originally Posted By DarkGray: That emoji was because you were being ripped off. Nexaph, which is the high end of reputable places, has ten vials of 10mg for ~$250. Originally Posted By DarkGray: Originally Posted By Asylum9: Originally Posted By ChuckD05: 10mg as in like $65/10mg vial? Yeah. It varied slightly but usually between $65-75 for a 10mg vial. Can't remember the name off hand, I'll look when I get home. Iirc it was an AUS based company but everything shipped from TX. There still in business but no longer ship to the USA. Found it. It was peptilabresearch.co.m but appears to be a dead link now. Dunno why they closed down to the USA. Never had any issues & prices where great. That emoji was because you were being ripped off. Nexaph, which is the high end of reputable places, has ten vials of 10mg for ~$250. |
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Originally Posted By spyderboy03: Yeah, there is a group buy right now that is $77 for 10x10mg vials. $65-$75 is the going rate for group buys with resellers and China vendors being around $100-$125. group buys - require time & faith and you may get burned. Example: Includes M,P,& Endo testing. T - $55 for 10x30mg vials. R - $90 for 10x30mg vials. + shipping FYI, group is closed to new invites so don't ask, but keep researching. |
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Originally Posted By AWMCoalition: group buys - require time & faith and you may get burned. Example: Includes M,P,& Endo testing. T - $55 for 10x30mg vials. R - $90 for 10x30mg vials. + shipping FYI, group is closed to new invites so don't ask, but keep researching. |
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Originally Posted By hummerbk: Is it ok to load a syringe with my weekly TIRZ dose and use it 3 days later without refrigerating it? It would have the cap replaced after filling and be stored at room temperature for 3 to 4 days. It's not generally regarded as a good practice to pre load syringes. They aren't designed for storage of doses. |
Sic Semper Oppai
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Originally Posted By dragoontwo: It's not generally regarded as a good practice to pre load syringes. They aren't designed for storage of doses. Originally Posted By dragoontwo: Originally Posted By hummerbk: Is it ok to load a syringe with my weekly TIRZ dose and use it 3 days later without refrigerating it? It would have the cap replaced after filling and be stored at room temperature for 3 to 4 days. It's not generally regarded as a good practice to pre load syringes. They aren't designed for storage of doses. My question would be why not take the dose when you have access to the refrigerator? I'm not understanding your dosing schedule. |
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Originally Posted By SemperGumbi: I just started on tirzepatide and have already noticed a serious decrease in appetite and about a 6 pound weight loss in about a month. What is the cheapest way you guys have found to get TIRZ? group buys via telegram. Crypto payments, and be ready to wait. Go check out stairway to gray |
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Originally Posted By HappyCamel: Not a big deal with water based stuff. My question would be why not take the dose when you have access to the refrigerator? I'm not understanding your dosing schedule. You are absolutely correct. I didn't want my hunting buddies fingering my vial especially after gutting deer or crapping in the woods. I went to a pharmacist and got a 6" long pill bottle that holds my syringes, alcohol wipes and TIRZ bottle. I'll keep it in the fridge. They can look but not put dirty fingers all over my stuff. My dosing schedule is once weekly and my next dose falls mid hunt. |
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I tried to buy from peplair. I created an account but when trying to purchase i kept getting a denial. After contacting support i was told the banking side rejected me as a high risk! I tried everything,,,different browsers, emails, phone numbers. For some reason (support says they “don’t know why”) i cannot purchase anything on peplair. Anyone else have problems on that site? I need to find another site with comparable pricing. |
