User Panel
Originally Posted By 36trap: While not a fan, I guarantee there are bubba's from our side of the isle sending out holiday cards with kitted up families. My take away is we must crush the left and anyone who supports them from antifags to old blue hairs that have been punching the D ticket their entire lives. View Quote Attached File |
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Originally Posted By Cecenrse: For the sake of authenticity, I am posting my nursing school graduation photo around 26 y/o (second stint in college. the first I was an accounting major, but hated it and went back to college, lol). I improved with age...for a while, lol. This photo will self destruct in a specific period of time. View Quote 🥰🥰🥰 |
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Originally Posted By Ex_Sanguine_Nation: Mom. Army nurse, civilian RN for decades. 1951-2008. https://www.ar15.com/media/mediaFiles/11358/20201218_151047-1737113.jpg View Quote I have learned never to comment on someone's mom, other than she has a beautiful smile. Nurses rock!! |
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Riot Squad 2020 Magnificent Unicorn
I prefer dangerous freedom over peaceful slavery Envy was once considered to be one of the seven deadly sins before it became one of the most admired virtues under its new name, 'social justice. |
RS Callsign Mayhem Midget
SSgt Jason A Decker. 11/6/09 |
Originally Posted By Cecenrse: For the sake of authenticity, I am posting my nursing school graduation photo around 26 y/o (second stint in college. the first I was an accounting major, but hated it and went back to college, lol). I improved with age...for a while, lol. This photo will self destruct in a specific period of time. [/url] View Quote Humm....when does Tom Cruise go back to the set again.... |
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Mike_314....If there was communism in the desert, there would soon be a shortage of sand.
Riot Squad Member 2020: we will shit on your pillow Riot stream list on top of page 3047 |
Originally Posted By Cecenrse: I have learned never to comment on someone's mom, other than she has a beautiful smile. Nurses rock!! View Quote View All Quotes View All Quotes Originally Posted By Cecenrse: Originally Posted By Ex_Sanguine_Nation: Mom. Army nurse, civilian RN for decades. 1951-2008. https://www.ar15.com/media/mediaFiles/11358/20201218_151047-1737113.jpg I have learned never to comment on someone's mom, other than she has a beautiful smile. Nurses rock!! It's okay. That picture is ticking, as well. |
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Originally Posted By Cecenrse: For the sake of authenticity, I am posting my nursing school graduation photo around 26 y/o (second stint in college. the first I was an accounting major, but hated it and went back to college, lol). I improved with age...for a while, lol. This photo will self destruct in a specific period of time. https://www.AR15.Com/media/mediaFiles/406377/20201127_151912-1737097.jpg View Quote View All Quotes View All Quotes Originally Posted By Cecenrse: Originally Posted By Socalmopar: Yeah... I think. Still stuck on Black Sheath Dress & Heels and range of outright authenticity. For the sake of authenticity, I am posting my nursing school graduation photo around 26 y/o (second stint in college. the first I was an accounting major, but hated it and went back to college, lol). I improved with age...for a while, lol. This photo will self destruct in a specific period of time. https://www.AR15.Com/media/mediaFiles/406377/20201127_151912-1737097.jpg Trouble Failed To Load Title |
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Originally Posted By Cecenrse:
View Quote Oh please please please be something to set shit off. |
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Originally Posted By RSG:
View Quote So this is the tactic people should use when a brace is questioned..... |
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Mike_314....If there was communism in the desert, there would soon be a shortage of sand.
Riot Squad Member 2020: we will shit on your pillow Riot stream list on top of page 3047 |
Originally Posted By stoner01: Well.....would you rather be a rapist or murderer.... View Quote Originally Posted By hiyaboa: We’ve done skull fucking but the rest of the corpse... https://media3.giphy.com/media/MEcU4c9fdUPqqNNU8N/giphy.gif?cid=6c09b952cf9394b778455ae913518a7eb948cac9fe206ffe&rid=giphy.gif View Quote Ok what the hell did i stumble back into? |
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1(800)kbi 4cat
Montani Semper Libre Qoute : FCSD - Hold up! I could have tip toed around here with just my hand covering my ass, instead of jamming my thumb in my asshole? Y'all motherfuckers need a user manual or something. |
Originally Posted By stoner01: Well.....would you rather be a rapist or murderer.... View Quote View All Quotes View All Quotes Originally Posted By stoner01: Originally Posted By Socalmopar: This isn't about making money having sex with the corpses of commies you killed is it? Asking for a friend... Well.....would you rather be a rapist or murderer.... Is this one of those liberal socialist commie new definitions type questions where the meanings are opposite no matter the question? |
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Originally Posted By dbmers: There are a handful of regulars in GD that I wish would skydive into the middle of the ocean. One of them has a screen name that was mentioned in a comedy. I hate that guy I am going there less and less. I scan the first page for and LEGIT news. So many security cams made in China. Probably everyone I own is. One for sure I know has back doors for the company to access. Nit that they’ll see anything except my unused side yard and neighbors shed. View Quote There's one 2020 guy who uses certain memes in every thread that I was thinking about startin sumpin sumpin with but then I was like nah he's trying to create discord . |
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Originally Posted By Cecenrse: For the sake of authenticity, I am posting my nursing school graduation photo around 26 y/o (second stint in college. the first I was an accounting major, but hated it and went back to college, lol). I improved with age...for a while, lol. This photo will self destruct in a specific period of time. https://www.AR15.Com/media/mediaFiles/406377/20201127_151912-1737097.jpg View Quote Thats back when nurses dressed up all hot. I hate the scrubs and stupid ass crocs they all wear now. |
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i WaS hACked
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Originally Posted By Cecenrse: That makes you a more physically attractive, desirable and wealthy man who is able to pick and choose from potential mates when that time comes again. Working on one's self is NEVER a bad idea. Just my perspective. It's also the way I chose to live most of my adult life as well. The only problem is you may reach a point of self satisfaction that you begin to feel no one is worthy of your wit and other special qualities. View Quote You're too kind. I'm trying to make enough to buy a ranch in Texas! |
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Originally Posted By eesmith: Newest weekly roundup: https://contextualinsurgent.substack.com/p/weekly-insurgency-12172020 View Quote |
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This decision is a freedom calculus decided long ago by Colonists . . . . The freedom they fought for was not free of cost then, and it is not free now. - Honorable Judge Roger T. Benitez
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Originally Posted By Scoobysmak: I am sure I will regret the day I ask "can we go back to 2020 please".... View Quote View All Quotes View All Quotes Originally Posted By Scoobysmak: Originally Posted By AZNetEng: In more ways than we can even imagine. Not a single doubt in my mind. I am sure I will regret the day I ask "can we go back to 2020 please".... Knowing what we know of how 2020 unfolded, what would you do different going back to 2016 and taking another run at it? |
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“So, never give up. Continue to fight. You’ll either find a win here and there, or you’ll die fighting. I can accept either of those out comes”- March 31st, 2020 - Until Valhalla
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Originally Posted By RSG: i WaS hACked
https://pbs.twimg.com/card_img/1339890019658567681/Q3nl1Imx?format=jpg&name=small View Quote What a lyin snake. They're all lyin snakes |
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Originally Posted By RSG:
View Quote If there was ever a time to send in the JBTs it's now. Raid and seize those machines. |
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This decision is a freedom calculus decided long ago by Colonists . . . . The freedom they fought for was not free of cost then, and it is not free now. - Honorable Judge Roger T. Benitez
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Originally Posted By AZNetEng: So here is a thought provoking question for the Squad. Knowing what we know of how 2020 unfolded, what would you do different going back to 2016 and taking another run at it? View Quote Buying all the ammo I can find, and #yolo everything on Tesla and Microvision stocks! |
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Originally Posted By Cecenrse: I think I have stated in the past that I had several real concerns about the RNA SARS_COV2 vaccine. First, an RNA vaccine has never been developed and approved for use in humans before now. We've had many years do so, but suddenly they have rushed this procedure into reality in a matter of months, rather than years. I have serious concerns regarding insufficient clinical trials length and number of infected/non-infected participants, and no long term data regarding side effects/adverse reactions from the vaccine. That will not be known for years. There is also the question of infertility as a possibility, though likely remote, but still possible. Many people have questioned if RNA vaccinations could permanently alter the DNA of the vaccinated patients. Also remote, but theoretically a possibility. There is also a remote, but theoretic possibility that permanent changes could be passed on to your future offspring. If that occurred it would likely make them less resistant to spiked protein viruses. Anyway, the article does a better job of explaining all of these things since he is a better writer, and more knowledgeable than I am. I realize that many of you have jobs which will require you to be vaccinated, military, HCW's, airline employees, and others. I am posting this full article in the spoiler because it is easily understood by laypeople, for the most part. It is primarily regarding the RNA questions. Quick read and if anyone has questions I don't know the answer to, I will do my best to find out. @BethanyHatch The Vaccine is administered intramuscularly, not subcutaneous. Click To View Spoiler When people hear the words RNA vaccine, the first question that comes to the average person's mind is, "Will this vaccine permanently alter my DNA?" The second question is, "If the vaccine does alter my DNA, what are the potential long-term health impacts?" These are fair questions. Unfortunately, these questions are usually brushed aside, ignored, minimized, or discounted by the pharmaceutical ecosystem. This concern about genetic modification is normally answered by the following argument: RNA will not permanently alter your DNA because it is a temporary molecule that quickly becomes destroyed in the cell, and because it is fundamentally different than DNA. RNA does not integrate into DNA, and RNA doesn't remain in the cell permanently because the cell destroys the RNA relatively quickly. Therefore, there is no potential risk of an RNA vaccine genetically modifying a person's genome. On the surface, this seems like a rock-solid answer. It is the textbook response that would earn a 100% grade on an examination for a college-level molecular biology class. However, the cells in our body know nothing of the exams being taken by graduate students. First, let me briefly describe how an RNA vaccine works. Second, let me show you viable cellular pathways where an RNA vaccine could make its way into someone's permanent genetic material. An RNA vaccine works by turning a small portion of the cells in our body into a vaccine production factory. Both RNA and DNA are information carrying molecules. They carry instructions on how to build specific proteins. Our cells read this information, and then build proteins according to the instructions. In the case of an RNA vaccine, the delivered RNA instructions instruct our cells to build a near-perfect replica of a very specific protein that resides on the outside of the SARS-CoV-2 virus called the "Spike" protein. This Spike protein normally resides on the outside of the virus and functions as a tether that enables the virus to enter into a human cell. Because the Spike Protein resides on the outside of the virus, it's prime real estate for our immune system to target. Therefore, when you are administered an RNA vaccine, this RNA will enter a small portion of your cells, and these cells will start churning out a replica of the viral Spike protein. It's important to realize that your cells are not producing the entire virus, just a portion of the virus the Spike protein. Because it is foreign to the body, this cellularly produced Spike protein will then prompt your immune cells to learn how to develop antibodies that specifically recognize the Spike protein. At this point, you are "vaccinated" because you have acquired antibodies that recognize the virus (via the Spike protein), as well as memory cells that can produce more of the antibody should you be infected with the actual virus. If your body is exposed to the coronavirus, these antibodies will recognize the Spike protein on the outside of the virus. When the virus is coated in antibodies, it is "neutralized" and can no longer infect other cells. Most other vaccines work by administering the Spike protein directly into your body, or by introducing an attenuated or inactivated virus that contains the Spike protein. In these types of traditional vaccines, the Spike protein was previously made in a vaccine production facility. In an RNA vaccine, there is no Spike protein in the vaccine. Instead, the vaccine provides your cells with instructions on how to build the Spike protein. Essentially, your cells have become the vaccine production factory. After some time, this delivered RNA will be destroyed by our cells, and the cells will stop producing the Spike protein. Our body should be left unchanged, except for the presence of antibodies and immune cells which now recognize the Spike protein of the virus. In theory, this is how the vaccine should work. Sounds great on paper, doesn't it? Before jumping to reductionist conclusions, let's go one level deeper into molecular biology to answer the question of whether or not this extraneous RNA could potentially alter our DNA permanently. I believe the answer to this question is yes. It is well known that RNA can be "reverse transcribed" into DNA. Residing in our cells are enzymes called "reverse transcriptases". These enzymes convert RNA into DNA. Multiple sources for this class of enzymes exist within our cells. These reverse transcriptases are normally made by other viruses termed "retroviruses". HIV is a retrovirus and so is Hepatitis B, but there are many other retroviruses that fall in this category. In addition to these external viruses, there are viruses that are hard-wired into our genomic DNA called endogenous retroviruses (ERVs). These ERVs harbor instructions to produce reverse transcriptase. In addition to ERVs, there are mobile genetic elements residing in our DNA called LTR-retrotransposons that also encode for reverse transcriptase enzymes. To top it all off, reverse transcriptase is naturally used by our cells to extend the telomeres at the end of chromosomes. These endogenous reverse transcriptase enzymes can essentially take single-stranded RNA and convert it into double-stranded DNA. This DNA can then be integrated into the DNA in the nucleus through an enzyme termed DNA integrase. With so many sources of reverse transcriptase, it is quite probable that the RNA introduced into our cells via the vaccine could be reverse transcribed into a segment of double-stranded DNA, and then integrated into our core genetic material in the nucleus of the cell. A variety of specific conditions need to be present for this to occur, but it is possible if the right convergence occurs. Biology is messy and not always perfectly predictable, even when the "rules" are known a priori. Even though the initial vaccine is only introduced into a relatively small portion of our cells, if this reverse transcription process occurs in stem cells, then this genetically modified cell can be replicated and amplified to a larger portion of cells that make up the tissues of the body. Stem cells serve as a reservoir to produce new cells in perpetual fashion. In this way, over time, a larger percentage of our somatic cells can be replaced by these genetically modified stem-cell precursors. This type of genetically modified replacement of cells is seen in some patients who have received bone-marrow transplants from other patients. In these patients, even germline cells such as sperm can inherit these genetic modifications, even though the pathway for this germline modification is still not understood. In these patients, the so called "rules" that presumably prevented such an outcome were violated. I think most molecular biologists would look at my thesis and discount it as improbable, and I wouldn't argue with them too strongly. After all, if these reverse pathways from RNA to DNA were actively possible, wouldn't a normal infection by the virus cause the same problem? Wouldn't the RNA introduced by a viral infection of SARS-CoV-2 serve as a potential substrate for permanent genetic modification of cellular DNA, just like the RNA in the vaccine? I would answer that this possibility exists, too. However, I believe the probability of viral RNA undergoing this process is much smaller for several reasons. First, the viral RNA is packaged into viral particles which act like a shell. These RNA molecules are temporarily unpackaged from this shell while inside the cell to produce more viral RNA and viral proteins, which are quickly sequestered and repackaged into new viral particles. Also, viral RNA is inherently unstable due to sequence specific peculiarities unique to viral RNA, and is quickly recognized by cellular enzymes for destruction. Therefore, the amount of time available for reverse transcriptase to work on "bare" viral RNA is very low. In contrast to this, the RNA provided to cells via a vaccine has been altered in the lab to increase its stability such that it persists in the cell for a much longer time. A number of modifications are made to increase the stability and longevity of this vaccine-delivered RNA. This artificial engineering of RNA is designed to produce RNA that hangs around in the cell much longer than viral RNA, or even RNA that our cell normally produces for normal protein production. The purpose of this engineered longevity is to increase the production of Spike protein by our cells to maximize the efficacy of the vaccine. In addition, this RNA is not rapidly sequestered away into new viral particles. Therefore, the probability that a molecular pathway could be found that results in this RNA being converted over into DNA is much higher, in my opinion. This probability may be miniscule, and may not even be noticeable in in vitro experiments, or even in clinical trials across tens of thousands of patients. The odds of this occurring may be 1 in 1 followed by many zeros; however, that miniscule probability flies out the window when you understand that the average human body has 30 trillion cells, and the vaccine will be deployed in up to 7 billion people. If you multiply these small probabilities across these large numbers, the probability that this could occur in a modestly large number of people is very real. What happens if this occurs? There are two possible outcomes that are not mutually exclusive. First, modification of somatic cells, and in particular, stem cells, could result in a segment of the population with an increasing percentage of their tissues being converted over to genetically modified cells. These genetically modified cells will possess the genetic sequence to produce Spike Protein. Because Spike protein is a foreign protein to the human body, the immune systems of these individuals will attack the cells in their body which express this protein. These people will almost inevitably develop autoimmune conditions which are irreversible, since this foreign protein antigen is now permanently hardwired into the instructions contained in their DNA. The second possibility is based on a pathway being found that transfers this genetic modification to germline cells (egg and sperm). This is certainly a more remote possibility, but if it occurred, this insertional genetic mutation would find itself in all future generations stemming from this individual or individuals. Because this is a germline modification and not a somatic modification, this new genetic element will be present in every single cell of these individuals. This means that potentially every tissue in their body could express Spike protein. Because this protein is present from birth, the immune system will recognize this new protein as "self" rather than non-self (foreign). If these individuals are infected with coronavirus, their immune system would fail to recognize the Spike protein of the virus as foreign, and these individuals will have substantially reduced capacity to fend off the coronavirus. Therefore, over time over future generations, a growing percentage of the population would be more susceptible to severe infection by the coronavirus due to limited immune function. Now, none of the scenarios outlined above touch on the downstream risk of developing antibody dependent enhancement (ADE), which is a major problem with any vaccine developed for coronaviruses. ADE is a risk for any type of vaccine, including RNA vaccines. The current RNA vaccines being rushed forward have only been tested for a few months, and ADE would not rear its ugly head for several years, although it could occur sooner. Therefore, the current clinical trial data is not anywhere close to being sufficient to rule out the health risk of ADE. If ADE does occur in an individual, then their response to the virus could be fatal when they are actually exposed to the virus post-vaccination. To learn more about the possibility of ADE, click here to read my article > "Is A Coronavirus Vaccine a Ticking Timebomb." In addition to the risks mentioned above, another risk becomes apparent: If the cell is infected with either an external virus, or endogenous retrovirus, while the vaccine is active in the cell, this from the vaccine could be genetically spliced into the existing genome of another virus. This virus would then gain a functional Spike protein, which would then allow it to infect respiratory tissues and other organs of the body. This means that viruses that were normally isolated to certain tissues would suddenly gain the ability to infect a much wider range of tissues, making them more pathogenic or deadly. It's probably good to point out at this stage of the discussion that an RNA vaccine has never been approved for use in humans. This would be the first time in history that such an approach would be used on a massive scale. Approximately 50 clinical trials have been conducted on RNA vaccines for cancer treatment, and about a dozen RNA-based vaccines are under development for SARS-CoV-2. Two candidates, one from Pfizer/BioNTech (BNT162b2) and the other from Moderna (mRNA-1273), are the furthest along, and have shown decent efficacy in Phase III clinical trials (although I would argue strongly the sample sizes of infected individuals in both experiments were so small that making this efficacy claim is rather dubious at this stage). If you have read the news lately, these vaccines are being rushed headlong to be deployed on a massive scale with little attention being paid to the potential ramifications. My professional opinion is that since RNA vaccines are a new mode of delivering vaccines, they should be tested for 5-10 years to demonstrate that genetic modification is not a major concern. In addition, all coronavirus vaccines, regardless of type, should be tested for an equal duration to show that ADE is not a concern. It is absolutely impossible to rule out these safety concerns in less than a year. I only share this information so people are informed and can weigh the potential risks and benefits. The bottom line is the choice is up to you; however, for people to make such an important decision, they need to possess all of the information. View Quote |
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What we’ve inherited from our ancestors has never existed to this extent before. And if we fail to preserve it, it will never, ever exist again. So, we cannot fail…
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Originally Posted By AZNetEng: So here is a thought provoking question for the Squad. Knowing what we know of how 2020 unfolded, what would you do different going back to 2016 and taking another run at it? View Quote I would’ve gotten a divorce and moved out to the country right after my daughter was born in 2018. It would’ve saved my son and I no small amount of heartache. |
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This decision is a freedom calculus decided long ago by Colonists . . . . The freedom they fought for was not free of cost then, and it is not free now. - Honorable Judge Roger T. Benitez
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Originally Posted By Cecenrse: I think I have stated in the past that I had several real concerns about the RNA SARS_COV2 vaccine. First, an RNA vaccine has never been developed and approved for use in humans before now. We've had many years do so, but suddenly they have rushed this procedure into reality in a matter of months, rather than years. I have serious concerns regarding insufficient clinical trials length and number of infected/non-infected participants, and no long term data regarding side effects/adverse reactions from the vaccine. That will not be known for years. There is also the question of infertility as a possibility, though likely remote, but still possible. Many people have questioned if RNA vaccinations could permanently alter the DNA of the vaccinated patients. Also remote, but theoretically a possibility. There is also a remote, but theoretic possibility that permanent changes could be passed on to your future offspring. If that occurred it would likely make them less resistant to spiked protein viruses. Anyway, the article does a better job of explaining all of these things since he is a better writer, and more knowledgeable than I am. I realize that many of you have jobs which will require you to be vaccinated, military, HCW's, airline employees, and others. I am posting this full article in the spoiler because it is easily understood by laypeople, for the most part. It is primarily regarding the RNA questions. Quick read and if anyone has questions I don't know the answer to, I will do my best to find out. @BethanyHatch The Vaccine is administered intramuscularly, not subcutaneous. Click To View Spoiler When people hear the words RNA vaccine, the first question that comes to the average person's mind is, "Will this vaccine permanently alter my DNA?" The second question is, "If the vaccine does alter my DNA, what are the potential long-term health impacts?" These are fair questions. Unfortunately, these questions are usually brushed aside, ignored, minimized, or discounted by the pharmaceutical ecosystem. This concern about genetic modification is normally answered by the following argument: RNA will not permanently alter your DNA because it is a temporary molecule that quickly becomes destroyed in the cell, and because it is fundamentally different than DNA. RNA does not integrate into DNA, and RNA doesn't remain in the cell permanently because the cell destroys the RNA relatively quickly. Therefore, there is no potential risk of an RNA vaccine genetically modifying a person's genome. On the surface, this seems like a rock-solid answer. It is the textbook response that would earn a 100% grade on an examination for a college-level molecular biology class. However, the cells in our body know nothing of the exams being taken by graduate students. First, let me briefly describe how an RNA vaccine works. Second, let me show you viable cellular pathways where an RNA vaccine could make its way into someone's permanent genetic material. An RNA vaccine works by turning a small portion of the cells in our body into a vaccine production factory. Both RNA and DNA are information carrying molecules. They carry instructions on how to build specific proteins. Our cells read this information, and then build proteins according to the instructions. In the case of an RNA vaccine, the delivered RNA instructions instruct our cells to build a near-perfect replica of a very specific protein that resides on the outside of the SARS-CoV-2 virus called the "Spike" protein. This Spike protein normally resides on the outside of the virus and functions as a tether that enables the virus to enter into a human cell. Because the Spike Protein resides on the outside of the virus, it's prime real estate for our immune system to target. Therefore, when you are administered an RNA vaccine, this RNA will enter a small portion of your cells, and these cells will start churning out a replica of the viral Spike protein. It's important to realize that your cells are not producing the entire virus, just a portion of the virus the Spike protein. Because it is foreign to the body, this cellularly produced Spike protein will then prompt your immune cells to learn how to develop antibodies that specifically recognize the Spike protein. At this point, you are "vaccinated" because you have acquired antibodies that recognize the virus (via the Spike protein), as well as memory cells that can produce more of the antibody should you be infected with the actual virus. If your body is exposed to the coronavirus, these antibodies will recognize the Spike protein on the outside of the virus. When the virus is coated in antibodies, it is "neutralized" and can no longer infect other cells. Most other vaccines work by administering the Spike protein directly into your body, or by introducing an attenuated or inactivated virus that contains the Spike protein. In these types of traditional vaccines, the Spike protein was previously made in a vaccine production facility. In an RNA vaccine, there is no Spike protein in the vaccine. Instead, the vaccine provides your cells with instructions on how to build the Spike protein. Essentially, your cells have become the vaccine production factory. After some time, this delivered RNA will be destroyed by our cells, and the cells will stop producing the Spike protein. Our body should be left unchanged, except for the presence of antibodies and immune cells which now recognize the Spike protein of the virus. In theory, this is how the vaccine should work. Sounds great on paper, doesn't it? Before jumping to reductionist conclusions, let's go one level deeper into molecular biology to answer the question of whether or not this extraneous RNA could potentially alter our DNA permanently. I believe the answer to this question is yes. It is well known that RNA can be "reverse transcribed" into DNA. Residing in our cells are enzymes called "reverse transcriptases". These enzymes convert RNA into DNA. Multiple sources for this class of enzymes exist within our cells. These reverse transcriptases are normally made by other viruses termed "retroviruses". HIV is a retrovirus and so is Hepatitis B, but there are many other retroviruses that fall in this category. In addition to these external viruses, there are viruses that are hard-wired into our genomic DNA called endogenous retroviruses (ERVs). These ERVs harbor instructions to produce reverse transcriptase. In addition to ERVs, there are mobile genetic elements residing in our DNA called LTR-retrotransposons that also encode for reverse transcriptase enzymes. To top it all off, reverse transcriptase is naturally used by our cells to extend the telomeres at the end of chromosomes. These endogenous reverse transcriptase enzymes can essentially take single-stranded RNA and convert it into double-stranded DNA. This DNA can then be integrated into the DNA in the nucleus through an enzyme termed DNA integrase. With so many sources of reverse transcriptase, it is quite probable that the RNA introduced into our cells via the vaccine could be reverse transcribed into a segment of double-stranded DNA, and then integrated into our core genetic material in the nucleus of the cell. A variety of specific conditions need to be present for this to occur, but it is possible if the right convergence occurs. Biology is messy and not always perfectly predictable, even when the "rules" are known a priori. Even though the initial vaccine is only introduced into a relatively small portion of our cells, if this reverse transcription process occurs in stem cells, then this genetically modified cell can be replicated and amplified to a larger portion of cells that make up the tissues of the body. Stem cells serve as a reservoir to produce new cells in perpetual fashion. In this way, over time, a larger percentage of our somatic cells can be replaced by these genetically modified stem-cell precursors. This type of genetically modified replacement of cells is seen in some patients who have received bone-marrow transplants from other patients. In these patients, even germline cells such as sperm can inherit these genetic modifications, even though the pathway for this germline modification is still not understood. In these patients, the so called "rules" that presumably prevented such an outcome were violated. I think most molecular biologists would look at my thesis and discount it as improbable, and I wouldn't argue with them too strongly. After all, if these reverse pathways from RNA to DNA were actively possible, wouldn't a normal infection by the virus cause the same problem? Wouldn't the RNA introduced by a viral infection of SARS-CoV-2 serve as a potential substrate for permanent genetic modification of cellular DNA, just like the RNA in the vaccine? I would answer that this possibility exists, too. However, I believe the probability of viral RNA undergoing this process is much smaller for several reasons. First, the viral RNA is packaged into viral particles which act like a shell. These RNA molecules are temporarily unpackaged from this shell while inside the cell to produce more viral RNA and viral proteins, which are quickly sequestered and repackaged into new viral particles. Also, viral RNA is inherently unstable due to sequence specific peculiarities unique to viral RNA, and is quickly recognized by cellular enzymes for destruction. Therefore, the amount of time available for reverse transcriptase to work on "bare" viral RNA is very low. In contrast to this, the RNA provided to cells via a vaccine has been altered in the lab to increase its stability such that it persists in the cell for a much longer time. A number of modifications are made to increase the stability and longevity of this vaccine-delivered RNA. This artificial engineering of RNA is designed to produce RNA that hangs around in the cell much longer than viral RNA, or even RNA that our cell normally produces for normal protein production. The purpose of this engineered longevity is to increase the production of Spike protein by our cells to maximize the efficacy of the vaccine. In addition, this RNA is not rapidly sequestered away into new viral particles. Therefore, the probability that a molecular pathway could be found that results in this RNA being converted over into DNA is much higher, in my opinion. This probability may be miniscule, and may not even be noticeable in in vitro experiments, or even in clinical trials across tens of thousands of patients. The odds of this occurring may be 1 in 1 followed by many zeros; however, that miniscule probability flies out the window when you understand that the average human body has 30 trillion cells, and the vaccine will be deployed in up to 7 billion people. If you multiply these small probabilities across these large numbers, the probability that this could occur in a modestly large number of people is very real. What happens if this occurs? There are two possible outcomes that are not mutually exclusive. First, modification of somatic cells, and in particular, stem cells, could result in a segment of the population with an increasing percentage of their tissues being converted over to genetically modified cells. These genetically modified cells will possess the genetic sequence to produce Spike Protein. Because Spike protein is a foreign protein to the human body, the immune systems of these individuals will attack the cells in their body which express this protein. These people will almost inevitably develop autoimmune conditions which are irreversible, since this foreign protein antigen is now permanently hardwired into the instructions contained in their DNA. The second possibility is based on a pathway being found that transfers this genetic modification to germline cells (egg and sperm). This is certainly a more remote possibility, but if it occurred, this insertional genetic mutation would find itself in all future generations stemming from this individual or individuals. Because this is a germline modification and not a somatic modification, this new genetic element will be present in every single cell of these individuals. This means that potentially every tissue in their body could express Spike protein. Because this protein is present from birth, the immune system will recognize this new protein as "self" rather than non-self (foreign). If these individuals are infected with coronavirus, their immune system would fail to recognize the Spike protein of the virus as foreign, and these individuals will have substantially reduced capacity to fend off the coronavirus. Therefore, over time over future generations, a growing percentage of the population would be more susceptible to severe infection by the coronavirus due to limited immune function. Now, none of the scenarios outlined above touch on the downstream risk of developing antibody dependent enhancement (ADE), which is a major problem with any vaccine developed for coronaviruses. ADE is a risk for any type of vaccine, including RNA vaccines. The current RNA vaccines being rushed forward have only been tested for a few months, and ADE would not rear its ugly head for several years, although it could occur sooner. Therefore, the current clinical trial data is not anywhere close to being sufficient to rule out the health risk of ADE. If ADE does occur in an individual, then their response to the virus could be fatal when they are actually exposed to the virus post-vaccination. To learn more about the possibility of ADE, click here to read my article > "Is A Coronavirus Vaccine a Ticking Timebomb." In addition to the risks mentioned above, another risk becomes apparent: If the cell is infected with either an external virus, or endogenous retrovirus, while the vaccine is active in the cell, this from the vaccine could be genetically spliced into the existing genome of another virus. This virus would then gain a functional Spike protein, which would then allow it to infect respiratory tissues and other organs of the body. This means that viruses that were normally isolated to certain tissues would suddenly gain the ability to infect a much wider range of tissues, making them more pathogenic or deadly. It's probably good to point out at this stage of the discussion that an RNA vaccine has never been approved for use in humans. This would be the first time in history that such an approach would be used on a massive scale. Approximately 50 clinical trials have been conducted on RNA vaccines for cancer treatment, and about a dozen RNA-based vaccines are under development for SARS-CoV-2. Two candidates, one from Pfizer/BioNTech (BNT162b2) and the other from Moderna (mRNA-1273), are the furthest along, and have shown decent efficacy in Phase III clinical trials (although I would argue strongly the sample sizes of infected individuals in both experiments were so small that making this efficacy claim is rather dubious at this stage). If you have read the news lately, these vaccines are being rushed headlong to be deployed on a massive scale with little attention being paid to the potential ramifications. My professional opinion is that since RNA vaccines are a new mode of delivering vaccines, they should be tested for 5-10 years to demonstrate that genetic modification is not a major concern. In addition, all coronavirus vaccines, regardless of type, should be tested for an equal duration to show that ADE is not a concern. It is absolutely impossible to rule out these safety concerns in less than a year. I only share this information so people are informed and can weigh the potential risks and benefits. The bottom line is the choice is up to you; however, for people to make such an important decision, they need to possess all of the information. View Quote I'm not sure who wrote that, but it's not true. for one thing, the spike protein gets presented on the cell surface that took up the mRNA. This presentation of the foreign protein, signals the immune system to target the cell for degradation and destruction. free piece of the degraded cell with the spike protein can float around and trigger additional immune cells. because the cell gets targeted for destruction, there isn't anything left that will get replicated see the last references in my thread https://www.ar15.com/forums/general/science-based-stuff-on-the-NCoV-notes-on-usc-stanford-surveys-cats-can-infect-people-vaccines/5-2315669/ now, the astrazeneca vaccine is a dna vaccine, using a chimpanzee adenovirus as the carrier and infectious agent. the virus infects a cell, allowing the dna to enter the cell, and it gets translocated into the dna of the cell, where it gets transcribed into the mrna to trigger the immune response. I need to see more on what exactly the astrazeneca vaccine does, but I would much rather get the moderna, followed by the pfizer, vaccines, rather than the astrazeneca one at this time |
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Very stark and dark and conceivable 100% correct. Grim AF. Nothing most of us didn't grow up with, I suppose. Now we just have children of our own and a different perspective. I can see one of the nation's largest military bases from my back deck. Not much worry here as I have a front row seat to the fireworks. It would be over before I knew it. View Quote View All Quotes View All Quotes Very stark and dark and conceivable 100% correct. Grim AF. Nothing most of us didn't grow up with, I suppose. Now we just have children of our own and a different perspective. I can see one of the nation's largest military bases from my back deck. Not much worry here as I have a front row seat to the fireworks. It would be over before I knew it. Same, grew up with this in the 80's, I'm 600m from a primary target. Site has state by state data, maps are from 1990 with predicted full scale exchange. Click on your state. Sobering to say the least, but we've come a long way in ballistic missile defence since 1990. http://www.ki4u.com/webpal/d_resources/list.htm Example: This is the nuclear target map for Montana, but remember, fallout can go anywhere or everywhere (and probably will). After you have looked at this map look at the Information for Montana that follows it. This link will take you back to the Index of all the States DENSE PACK - Look at all those target sites. So close Together! It serves a purpose. It is missiles protecting missles, and this is how it is done. These are "hardened" sites. Meaning it takes a direct ground explosion to dig them out. An air burst will not do it. When you have a ground explosion it throws many tons of dust and sand up into the air. High into the air. This is what will later become fallout carried by the winds hundreds, sometimes thousands, of miles away. But right over that site that has just been hit the sand and grit in the air is very thick for quite a while. Another high speed missile (ICBM) trying to come through it will have its skin torn off just like by sand blasting and it will be destroyed. So the other missile sites nearby are safe. On the other hand, because missiles take off much slower than the speeds they eventually reach, the missiles in the undamaged silos can still be launched and will pass through the dust cloud without be harmed. Neat, eh? See there is a purpose in putting so many in one place. Now the only way that you can dig them out is with what is called a slow walk. Hit a target. Move on further and hit another target where the dust from the first won't hurt you. Come back thirty or forty-five minutes later and hit a second target near where you hit the first, after the cloud has had time to blow away. A slow process. Some silos will already have launched and you will waste the shot. Others can still wait to launch later because you can only get one at a time. This could go on for days. Neat. The military missiles protecting missiles. But they don't protect you, because if you are downwind you will get the fallout. Fatal if you are not in a shelter. They call it Defense but it is only Destruction. Nothing here defends or protects you, if they are used. |
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It's not stupid, it's advanced!!
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Originally Posted By cm: I'm not sure who wrote that, but it's not true. for one thing, the spike protein gets presented on the cell surface that took up the mRNA. This presentation of the foreign protein, signals the immune system to target the cell for degradation and destruction. free piece of the degraded cell with the spike protein can float around and trigger additional immune cells. because the cell gets targeted for destruction, there isn't anything left that will get replicated see the last references in my thread https://www.ar15.com/forums/general/science-based-stuff-on-the-NCoV-notes-on-usc-stanford-surveys-cats-can-infect-people-vaccines/5-2315669/ now, the astrazeneca vaccine is a dna vaccine, using a chimpanzee adenovirus as the carrier and infectious agent. the virus infects a cell, allowing the dna to enter the cell, and it gets translocated into the dna of the cell, where it gets transcribed into the mrna to trigger the immune response. I need to see more on what exactly the astrazeneca vaccine does, but I would much rather get the moderna, followed by the pfizer, vaccines, rather than the astrazeneca one at this time View Quote Copy & pasting from Pfizers power point info pack; Lipid nanoparticle-formulated mRNA vaccine encoding the spike protein – Spike protein: facilitates entry of virus into cells Vaccination induces antibodies that can block entry of SARS-CoV-2 into cells, thereby preventing infection FDA issued an Emergency Use Authorization on December 13, 2020 for use in persons aged ≥16 years mRNA vaccines take advantage of the process that cells use to make proteins in order to trigger an immune response – Like all vaccines, COVID-19 mRNA vaccines have been rigorously tested for safety before being authorized for use in the United States –mRNA technology is new, but not unknown. They have been studied for more than a decade –mRNA vaccines do not contain a live virus and do not carry a risk of causing disease in the vaccinated person –mRNA from the vaccine never enters the nucleus of the cell and does not affect or interact with a person’s DNA 2-dose series administered intramuscularly 3 weeks apart Administration of 2nd dose within 4-day grace period (e.g., day 17-21) considered valid If >21 days since 1st dose, 2nd dose should be administered at earliest opportunity (but no doses need to be repeated) Both doses are necessary for protection; efficacy of a single dose has not been systematically evaluated Pfizer-BioNTech COVID-19 vaccine not interchangeable with other COVID-19 vaccine products – Safety and efficacy of a mixed series has not been evaluated Persons initiating series with Pfizer-BioNTech COVID-19 vaccine should complete series with same product If two doses of different mRNA COVID-19 vaccine products inadvertently administered, no additional doses of either vaccine recommended at this time – Recommendations may be updated as further information becomes available or additional vaccine types authorized Pfizer-BioNTech COVID-19 vaccine should be administered alone with a minimum interval of 14 days before or after administration with any other vaccines – Due to lack of data on safety and efficacy of the vaccine administered simultaneously with other vaccines If Pfizer-BioNTech COVID-19 vaccine is inadvertently administered within 14 days of another vaccine, doses do not need to be repeated for either vaccine |
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KF7WNX If you want a picture of the future, imagine Clownshoes stomping on a human face—for ever.
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Originally Posted By AZNetEng: So here is a thought provoking question for the Squad. Knowing what we know of how 2020 unfolded, what would you do different going back to 2016 and taking another run at it? View Quote View All Quotes View All Quotes Originally Posted By AZNetEng: Originally Posted By Scoobysmak: Originally Posted By AZNetEng: In more ways than we can even imagine. Not a single doubt in my mind. I am sure I will regret the day I ask "can we go back to 2020 please".... Knowing what we know of how 2020 unfolded, what would you do different going back to 2016 and taking another run at it? Bought cans for every caliber I shoot. And doubled what I considered stacking it deep when buying it cheap. |
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Originally Posted By AlmightyTallest: Same, grew up with this in the 80's, I'm 600m from a primary target. https://i.pinimg.com/originals/e0/f7/df/e0f7df02b1ee091151b9a0e625e4ead7.jpg Site has state by state data, maps are from 1990 with predicted full scale exchange. Click on your state. Sobering to say the least, but we've come a long way in ballistic missile defence since 1990. http://www.ki4u.com/webpal/d_resources/list.htm Example: http://www.ki4u.com/webpal/d_resources/states/mt.jpg so i'll be pulling a mayor of hiroshima if one hits cumberland View Quote |
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1(800)kbi 4cat
Montani Semper Libre Qoute : FCSD - Hold up! I could have tip toed around here with just my hand covering my ass, instead of jamming my thumb in my asshole? Y'all motherfuckers need a user manual or something. |
I want to be clear that I don't want to start a vaccine fight here,
I'm just saying based on the science, the mRNA vaccine doesn't get into the nucleus and gets replicated when the cell replicates, because the cell that took up the mRNA gets targeted for destruction |
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Originally Posted By dmjung: Bought cans for every caliber I shoot. And doubled what I considered stacking it deep when buying it cheap. View Quote View All Quotes View All Quotes Originally Posted By dmjung: Originally Posted By AZNetEng: Originally Posted By Scoobysmak: Originally Posted By AZNetEng: In more ways than we can even imagine. Not a single doubt in my mind. I am sure I will regret the day I ask "can we go back to 2020 please".... Knowing what we know of how 2020 unfolded, what would you do different going back to 2016 and taking another run at it? Bought cans for every caliber I shoot. And doubled what I considered stacking it deep when buying it cheap. I was more thinking along the lines of fixing the voting system as a whole, but I have to agree with this. I would have burned through both CC even before I was admitted for my heart transplant not knowing I would make it..... I still saved over $900 buy getting a TS USA prime account.... |
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Mike_314....If there was communism in the desert, there would soon be a shortage of sand.
Riot Squad Member 2020: we will shit on your pillow Riot stream list on top of page 3047 (3613 noted for me) |
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Originally Posted By MRTsHaircut: True. But not connections with a foreign citizen or government.... View Quote View All Quotes View All Quotes Originally Posted By MRTsHaircut: Originally Posted By 30calTBLkid: I have seen some people get away with crazy shit because they disclosed it on an sf86 and their ci rep had been advised when the "event" happened. True. But not connections with a foreign citizen or government.... Foriegn governments I've never seen. Foriegn citizens, absolutely, as long as its disclosed to the CI rep in your CoC. I've seen dudes disclose anything from keeping up with a former Afghan interpreter on social media to straight up honey pot shit. As long as they disclosed it, it was updated if reoccurring, didn't enter into a business agreement, no money changed hands, they weren't disclosing secrets, etc., its not that big of a deal. Even banging the local honey pot is survivable. Now if you were married, and doing the wrong thing? Done for. |
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"Never underestimate the tenacity of folks without the distraction of internet pornography." -TxRabbitBane
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Originally Posted By eesmith: Newest weekly roundup: https://contextualinsurgent.substack.com/p/weekly-insurgency-12172020 View Quote BTW y’all will definitely want to read this one, I discussed the Portland “Red House” eviction battle and I found a massive repository of lefty docs and guides, including things like the DHS crowd control manual. Just one folder: Attached File Part of a barricade guide: Attached File |
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Originally Posted By 30calTBLkid: Foriegn governments I've never seen. Foriegn citizens, absolutely, as long as its disclosed to the CI rep in your CoC. I've seen dudes disclose anything from keeping up with a former Afghan interpreter on social media to straight up honey pot shit. As long as they disclosed it, it was updated if reoccurring, didn't enter into a business agreement, no money changed hands, they weren't disclosing secrets, etc., its not that big of a deal. Even banging the local honey pot is survivable. Now if you were married, and doing the wrong thing? Done for. View Quote Yep, I've done that my self as I still keep up with the two who came here, and now they're citizens. |
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KF7WNX If you want a picture of the future, imagine Clownshoes stomping on a human face—for ever.
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Originally Posted By Cecenrse: For the sake of authenticity, I am posting my nursing school graduation photo around 26 y/o (second stint in college. the first I was an accounting major, but hated it and went back to college, lol). I improved with age...for a while, lol. This photo will self destruct in a specific period of time. https://www.AR15.Com/media/mediaFiles/406377/20201127_151912-1737097.jpg View Quote |
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What we’ve inherited from our ancestors has never existed to this extent before. And if we fail to preserve it, it will never, ever exist again. So, we cannot fail…
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Originally Posted By eesmith: BTW y’all will definitely want to read this one, I discussed the Portland “Red House” eviction battle and I found a massive repository of lefty docs and guides, including things like the DHS crowd control manual. Just one folder: https://www.AR15.Com/media/mediaFiles/214740/668F6CEB-1576-4968-8FD5-F467B01BAA11_png-1737247.JPG Part of a barricade guide: https://www.AR15.Com/media/mediaFiles/214740/E9318F6D-6F12-4A36-887D-E144CF1565C2_jpe-1737244.JPG View Quote Interesting that there are some random Chinese characters on the barricade guide image. |
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What we’ve inherited from our ancestors has never existed to this extent before. And if we fail to preserve it, it will never, ever exist again. So, we cannot fail…
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Originally Posted By AZNetEng: So here is a thought provoking question for the Squad. Knowing what we know of how 2020 unfolded, what would you do different going back to 2016 and taking another run at it? View Quote View All Quotes View All Quotes Originally Posted By AZNetEng: Originally Posted By Scoobysmak: Originally Posted By AZNetEng: In more ways than we can even imagine. Not a single doubt in my mind. I am sure I will regret the day I ask "can we go back to 2020 please".... Knowing what we know of how 2020 unfolded, what would you do different going back to 2016 and taking another run at it? |
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What we’ve inherited from our ancestors has never existed to this extent before. And if we fail to preserve it, it will never, ever exist again. So, we cannot fail…
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What we’ve inherited from our ancestors has never existed to this extent before. And if we fail to preserve it, it will never, ever exist again. So, we cannot fail…
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Spoke with a good friend of ours last night in Oklahoma. Her whole family are preppers and are very conservative. Her brother is a county sheriff outside of Oklahoma City on the I-35 strip. He said that over the last four weeks he has stopped multiple cars per week with military age Chinese nationals for speeding. Usually 3-4 in a car. Several times he has had to use an interpreter to even communicate. Up until last month, he has never stopped a car load like this before in 10 years. Several said they were looking to purchase agricultural land. Anyway, he has been reporting to DHS. Just found it interesting and thought I would share.
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Originally Posted By AlmightyTallest: Same, grew up with this in the 80's, I'm 600m from a primary target. https://i.pinimg.com/originals/e0/f7/df/e0f7df02b1ee091151b9a0e625e4ead7.jpg Site has state by state data, maps are from 1990 with predicted full scale exchange. Click on your state. Sobering to say the least, but we've come a long way in ballistic missile defence since 1990. http://www.ki4u.com/webpal/d_resources/list.htm Example: http://www.ki4u.com/webpal/d_resources/states/mt.jpg View Quote Just finished reading some of that. I am eh not good but not terrible either based on the maps. I just have one thing to say, if we are at war and China or someone else kills the commies before I do I will be pissed.... ETA...before I get reported.....I was kidding on the last line.... |
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Mike_314....If there was communism in the desert, there would soon be a shortage of sand.
Riot Squad Member 2020: we will shit on your pillow Riot stream list on top of page 3047 (3613 noted for me) |
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